FullText URL JOS_24_2_377.pdf
Author Omori, Toshinori| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Takeda, Ken| Hasei, Joe| Yoshida, Aki| Yanai, Hiroyuki| Ozaki, Toshifumi|
Published Date 2019-03
Publication Title Journal of Orthopaedic Science
Volume volume24
Issue issue2
Publisher Elsevier
Start Page 377
End Page 381
ISSN 0949-2658
NCID AA11627828
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2016 The Japanese Orthopaedic Association
File Version author
PubMed ID 28187993
DOI 10.1016/j.jos.2016.12.011
Web of Science KeyUT 000460662100033
Related Url isVersionOf https://doi.org/10.1016/j.jos.2016.12.011
FullText URL JOS_24_2_337.pdf
Author Fujiwara, Tomohiro| Kunisada, Toshiyuki| Takeda, Ken| Hasei, Joe| Nakata, Eiji| Mochizuki, Yusuke| Kiyono, Masahiro| Yoshida, Aki| Ozaki, Toshifumi|
Published Date 2019-03
Publication Title Journal of Orthopaedic Science
Volume volume24
Issue issue2
Publisher Elsevier
Start Page 337
End Page 341
ISSN 0949-2658
NCID AA11627828
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2018 The Japanese Orthopaedic Association.
File Version author
PubMed ID 30857616
DOI 10.1016/j.jos.2018.09.017
Web of Science KeyUT 000460662100026
Related Url isVersionOf https://doi.org/10.1016/j.jos.2018.09.017
JaLCDOI 10.18926/AMO/48560
FullText URL 66_3_213.pdf
Author Kataoka, Masaki| Kunisada, Toshiyuki| Tanaka, Masato| Takeda, Ken| Itani, Satoru| Sugimoto, Yoshihisa| Misawa, Haruo| Senda, Masuo| Nakahara, Shinnosuke| Ozaki, Toshifumi|
Abstract There are a variety of treatment options for patients with spinal metastasis, and predicting prognosis is essential for selecting the proper treatment. The purpose of the present study was to identify the significant prognostic factors for the survival of patients with spinal metastasis. We retrospectively reviewed 143 patients with spinal metastasis. The median age was 61 years. Eleven factors reported previously were analyzed using the Cox proportional hazards model:gender, age, performance status, neurological deficits, pain, type of primary tumor, metastasis to major organs, previous chemotherapy, disease-free interval before spinal metastasis, multiple spinal metastases, and extra-spinal bone metastasis. The average survival of study patients after the first visit to our clinic was 22 months. Multivariate survival analysis demonstrated that type of primary tumor (hazard ratio [HR]=6.80, p<0.001), metastasis to major organs (HR=2.01, p=0.005), disease-free interval before spinal metastasis (HR=1.77, p=0.028), and extra-spinal bone metastasis (HR=1.75, p=0.017) were significant prognostic factors. Type of primary tumor was the most powerful prognostic factor. Other prognostic factors may differ among the types of primary tumor and may also be closely associated with primary disease activity. Further analysis of factors predicting prognosis should be conducted with respect to each type of primary tumor to help accurately predict prognosis.
Keywords spine metastasis survival prognostic factor cancer
Amo Type Original Article
Published Date 2012-06
Publication Title Acta Medica Okayama
Volume volume66
Issue issue3
Publisher Okayama University Medical School
Start Page 213
End Page 219
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22729101
Web of Science KeyUT 000305669700004