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ID 12021
Eprint ID
12021
FullText URL
Thumnail K003356.pdf 211 KB
Title Alternative
ラット舌咽及び迷走神経におけるASIC3含有1次知覚ニューロンの分布
Author
Fukuda, Tomoki
Abstract
ASIC3-immunoreactivity (ir) was examined in the rat vagal and glossopharyngeal sensory ganglia. In the jugular, petrosal and nodose ganglia, 24.8%, 30.8% and 20.6% of sensory neurons, respectively, were immunoreactive for ASIC3. These neurons were observed throughout the ganglia. A double immunofluorescence method demonstrated that many ASIC3-immunoreactive (ir) neurons co-expressed calcitonin gene-related peptide (CGRP)- or vanilloid receptor subtype 1 (VRL-1)-ir in the jugular (CGRP, 77.8%; VRL-1, 28.0%) and petrosal ganglia (CGRP, 61.7%; VRL-1, 21.5%). In the nodose ganglion, however, such neurons were relatively rare (CGRP, 6.3%; VRL-1, 0.4%). ASIC3-ir neurons were mostly devoid of tyrosine hydroxylase in these ganglia. However, some ASIC3-ir neurons co-expressed calbindin D-28k in the petrosal (5.5%) and nodose ganglia (3.8%). These findings may suggest that ASIC3-containing neurons have a wide variety of sensory modalities in the vagal and glossopharyngeal sensory ganglia.
Keywords
ASIC3
CGRP
Jugular ganglion
Nodose ganglion
Petrosal ganglion
VRL-1
Note
http://dx.doi.org/10.1016/j.brainres.2006.01.039
Published Date
2006-03-24
Publication Title
Content Type
Thesis or Dissertation
Grant Number
甲第3356号
Granted Date
2006-03-24
Thesis Type
博士(歯学)
Grantor
岡山大学
Official Url
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16510130&dopt=Abstract
language
日本語
File Version
none
Refereed
Unknown