JaLCDOI 10.18926/AMO/32641
FullText URL fulltext.pdf
Author Ozaki, Toshifumi| Inoue, Hajime| Taguchi, Kohji| Sugihara, Shinsuke|
Abstract <p>We compared gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) enhanced T1-weighted images (T1-Gd) with the histopathological findings in 13 patients with bone or soft tissue sarcomas. Signal intensity of the viable tumor tissue was increased in T1-Gd in 92% of the patients. The necrotic or cystic areas in the tumor were not enhanced, rendering them distinctly. The degree of enhancement of the edematous area around the tumor was similar to or more marked than that of the tumor in 54% of the patients. Area showing inflammatory cells infiltration and edematous areas in the tumor tissue were also enhanced. Thus, the effect of preoperative chemotherapy in tumor tissues other than necrotic and cystic areas tended to be underestimated in T1-Gd. Its effect should be comprehensively evaluated based on not only T1-Gd but also T2-weighted images and findings of other imaging techniques.</p>
Keywords gadolinium diethylenetriaminepentaacetic acid(DTPA) magnetic resonance(MR) bone neoplasms soft tissue neoplasms
Amo Type Article
Published Date 1992-12
Publication Title Acta Medica Okayama
Volume volume46
Issue issue6
Publisher Okayama University Medical School
Start Page 471
End Page 477
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 1485542
Web of Sience KeyUT A1992KE49600010
Author Hamazaki, Yukio| Ogawa, Katsuo| Tsutsumi, Akira| Ohmori, Masaki| Taguchi, Kohji|
Published Date 1963-02
Publication Title Acta Medicinae Okayama
Volume volume17
Issue issue1
Content Type Journal Article
Author Takechi, Hideo| Taguchi, Kohji|
Published Date 1978-10
Publication Title Acta Medica Okayama
Volume volume32
Issue issue5
Content Type Journal Article
JaLCDOI 10.18926/AMO/30784
FullText URL fulltext.pdf
Author Kunisada, Toshiyuki| Kawai, Akira| Ozaki, Toshifumi| Sugihara, Shinsuke| Taguchi, Kohji| Inoue, Hajime|
Abstract <p>In this study, we reviewed the clinical features of 11 patients with malignant schwannoma who were treated in our institute. Five patients had coexistent von Recklinghausen's disease and one of them showed multifocal occurrence. Patients with the centrally located tumors had a poorer prognosis than those with the others. The overall 3-year survival rate was 36%; 40% in patients with von Recklinghausen's disease and 33% in the others. At the time of the last follow-up, 9 patients had died of the tumor, one continued to be tumor free, and one was alive with tumor. Postoperative local recurrence developed in 5 patients (45%); 4 out of 6 patients (67%) who underwent a marginal excision and one out of 3 (33%) who underwent primary amputation. There was no local recurrence in patients after a wide excision with at least 3cm of normal tissue removed surrounding the tumor in all directions. Nine patients (82%) developed pulmonary metastasis. The effect of adjuvant chemotherapy was not clear in this study. The high risk of pulmonary metastasis in this disease indicates the necessity of more effective adjuvant chemotherapy.</p>
Keywords malignant schwannoma clinical analysis von Recklinghausen's disease
Amo Type Article
Published Date 1997-04
Publication Title Acta Medica Okayama
Volume volume51
Issue issue2
Publisher Okayama University Medical School
Start Page 87
End Page 92
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 9142345
Web of Sience KeyUT A1997WX19600005
JaLCDOI 10.18926/AMO/30472
FullText URL fulltext.pdf
Author Uchida, Yoichiro| Kawai, Akira| Taguchi, Kohji| Yokoi, Tadashi| Pu, Jian| Inoue, Hajime|
Abstract <p>We conducted a clinicopathological analysis of chondrosarcomas in 17 patients treated in our institute. The 5- and 10-year overall survival rates of the patients were 72.3% and 61.9%, respectively. The significant prognostic factors were size and histologic grade of the tumor. Sex, age, location of the primary tumor, or the presence of a preceding exostosis did not affect the treatment results significantly. Chondrosarcomas of histologic grades I and II did not metastasize, while all grade III and dedifferentiated chondrosarcomas metastasized to the lung. The local recurrence rate depended on the surgical margin. Wide excision with an adequate surgical margin is important to achieve local control of the chondrosarcoma.</p>
Keywords chondrosarcoma pathological grading prognostic factors
Amo Type Article
Published Date 1996-08
Publication Title Acta Medica Okayama
Volume volume50
Issue issue4
Publisher Okayama University Medical School
Start Page 191
End Page 196
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 8874580
Web of Sience KeyUT A1996VE60800002