JaLCDOI 10.18926/AMO/31942
FullText URL fulltext.pdf
Author Nakamoto, Shu| Sadahira, Yoshito| Mori, Masaharu| Awai, Michiyasu|
Abstract <p>We investigated the organ distribution of four types of red blood cells (RBC) preparations: native RBC, asialo-RBC, native ghosts and asialo-ghosts. Intravenously injected asialo-ghosts were rapidly removed from the blood stream and accumulated mainly in the liver 120 min after the injection. Our results suggest that asialo-ghosts are a simple and effective carrier for targeting of drugs to the liver.</p>
Keywords red blood cell ghosts sialidase-treatment orgam distribution targeting to liver.
Amo Type Article
Published Date 1986-02
Publication Title Acta Medica Okayama
Volume volume40
Issue issue1
Publisher Okayama University Medical School
Start Page 61
End Page 64
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 3008506
Web of Sience KeyUT A1986A190200009
JaLCDOI 10.18926/AMO/30673
FullText URL fulltext.pdf
Author Mori, Masaharu| Nakamoto, Shu| Kirizuka, Keizi| Sadahira, Yoshito| Awai, Michiyasu| Seno, Satimaru| Sasaki, Junzo| Utsumi, Kozo|
Abstract <p>Cytochalasin B (CB) treatment induces or accelerates the capping phenomenon in some cells. In Ehrlich ascites tumor cells (EATC) CB treatment apparently induced the capping of Con A binding sites as observed under a fluorescent microscope. However, electron microscopic examinations revealed that the CB treatment did not induce a rearrangement of Con A binding sites, but rather it only induced a change in cell shape. On the contrary, CB treatment inhibited the capping phenomenon induced by treatment with Con A. Electron microscopic observations may give exact information on the distribution of lectin binding sites.</p>
Keywords Ehrlich ascites tumor cell concanvalin A cytochalasin B cap formation
Amo Type Brief Note
Published Date 1982-12
Publication Title Acta Medica Okayama
Volume volume36
Issue issue6
Publisher Okayama University Medical School
Start Page 483
End Page 486
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
File Version publisher
Refereed True
PubMed ID 7158429
Web of Sience KeyUT A1982PW07500007