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ID 52900
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Author
Muro, Shinichiro
Nasu, Junichiro
Harada, Ryo
Matsubara, Minoru
Nakarai, Asuka
Uno, Masatoshi
Abstract
A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and serum tumor markers. Fine needle aspiration revealed Grade 3 small-cell type primary pancreatic neuroendocrine carcinoma. Consequently, the diagnosis of malignant insulinoma was made. Transarterial embolization (TAE) for hepatic metastases resulted in the reduction of tumor volume and prompt resolution of hypoglycemic attacks, whereas diazoxide and systemic chemotherapy had been ineffective for controlling blood glucose levels, and octreotide was unavailable due to the allergic effect. This case report highlights the potential usefulness of TAE for malignant insulinomas in the management of hypoglycemia.
Keywords
malignant insulinoma
hypoglycemia
liver metastases
transarterial embolization
neuroendocrinetumor
Amo Type
Case Report
Published Date
2014-10
Publication Title
Acta Medica Okayama
Volume
volume68
Issue
issue5
Publisher
Okayama University Medical School
Start Page
307
End Page
311
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2014 by Okayama University Medical School
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publisher
Refereed
True
PubMed ID
Web of Sience KeyUT