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ID 15917
Eprint ID
15917
FullText URL
Thumnail 100_405.pdf 922 KB
Title Alternative
Studies on lipids and fatty acids in rats with streptozotocin-induced insulin deficiency II. Incorporation of 1-(14)C-sodium acetate into lipids and fatty acids of liver slices and whole blood cells
Author
Miyake, Kanji
Abstract
In order to study the lipid and fatty acid metabolism in the insulin deficient state, the in vitro incorporation of 1-(14)C-sodium acetate into major lipid fractions and fatty acids of liver slices and whole blood cells was determined. Rats were studied one week, one month and three months after insulin deficiency was induced by administration of streptozotocin.The net incorporation of (14)C into lipid fractions and total fatty acids of liver slices significantly decreased after one week. On the other hand the net incorporation of (14)C into the lipid fractions and total fatty acids of whole blood cells showed a tendency to decrease after three months.The net (14)C incorporation into free cholesterol decreased significantly and that into phospholipids increased significantly in liver slices after one week. The net (14)C incorporation into free cholesterol of whole blood cells decreased significantly on the same day.A significant decrease in the percent incorporation of (14)C into oleic acid was observed in both liver slices and whole blood cells after one month and three months.
Keywords
streptozotocin
肝スライス
全血細胞
(14)Cの取り込み
Published Date
1988
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume100
Issue
issue3-4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
405
End Page
418
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/100/3-4/100_3-4_405/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma