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ID 16426
Eprint ID
16426
FullText URL
Thumnail 96_511.pdf 335 KB
Title Alternative
Study on the role of catalase for uptake of metallic mercury Part 4 In vitro reduction of mercuric ion by superoxide anion, NADPH, NADH and acatalasemic mouse liver homogenate
Author
Kenmotsu, Katashi
Abstract
In vitro reduction of mercuric ion to metallic mercury by superoxide anion, NADPH, NADH and acatalasemic mouse liver homogenate was investigated. Superoxide anion generated by the xanthine-xanthine oxidase system reduced mercuric ion to metallic mercury in vitro. The reduction rate was inceresed linearly by the increasing concentration of xanthine oxidase. The reduction of mercuric ion by superoxide anion was increased by the addition of cytochrome c and nitro blue tetrazolium. The reduction of mercuric ion was inhibited in the presence of superoxide dismutase and catalase. The rate of reduction of mercuric ion by acatalasemic mouse liver homogenates was higher than that by normal mice liver homogenate. The reduction of mercuric ion by mouse liver homogenate was inhibited by the generation of superoxide anion, but the reduction rate by acatalasemic mouse liver homogenate was higher than that of normal mouse homogenate. NADPH and NADH reduced mercuric ion to metallic mercury. The reduction decreased in the presence of mouse liver homogenate. These results indicate that metabolism of mercury is influenced by the balance of oxidation and reduction systems
Keywords
reduction of mercuric ion
superoxide anion
NADPH
NADH
catalase
Published Date
1984-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume96
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
511
End Page
517
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/96/5-6/96_5-6_511/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma