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ID 32954
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Author
Asaumi, Jun-ichi
Konouchi, Hironobu
Kishi, Kanji
Abstract

Because malignant lymphoma, the second most common malignant tumor of the head and neck, and squamous cell carcinoma (SCC), the most common malignant tumor of the head and neck, require different treatments, it is important to be able to differentiate them. In the present study, we attempted to differentiate malignant lymphomas from SCCs using dynamic contrast-enhanced MRI (DCE-MRI). Seventeen lesions (in 8 cases) of malignant lymphoma and 30 cases of SCC were compared by DCE-MRI.

Thirteen of 17 malignant lymphomas (76.5%) showed the maximum contrast index (CI) at 90–180 s, while 26 of 30 SCCs (86.7%) showed the maximum CI at a much faster 60–105 s. There was a statistically significant difference between SCC and malignant lymphoma in the time needed reach the maximum CI (p=0.0177). There was also significant difference between SCC and malignant lymphoma in their maximum CIs (p<0.001), with the maximum CIs of 29/30 SCCs (96.7%) above 2.0, while 12/17 malignant lymphomas (70.6%) showed CIs of less than 2.0. We consider these findings to be useful for distinguishing lymphomas from SCCs.

Keywords
DCE-MRI
Head and neck
Lymphoma
Squamous cell carcinoma
Contrast index curve
Note
Digital Object Identifer: 10.1016/j.oraloncology.2003.12.002
Published with permission from the copyright holder. This is the author's copy, as published in Oral Oncology, July 2004, Volume 40, Issue 6, Pages 579-584.
Publisher URL: http://dx.doi.org/10.1016/j.oraloncology.2003.12.002
Direct access to Thomson Web of Science record
Copyright © 2003 Elsevier. Ltd. All rights reserved.
Published Date
2004-7
Publication Title
Oral Oncology
Volume
volume40
Issue
issue6
Start Page
579
End Page
584
Content Type
Journal Article
language
英語
Refereed
True
DOI
Web of Sience KeyUT
Submission Path
dentistry_general/5