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ID 55346
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Nishimori, Hisakazu Department of Transfusion Medicine, Okayama University Hospital
Fujii, Nobuharu Department of Transfusion Medicine, Okayama University Hospital
Fujii, Keiko Department of Transfusion Medicine, Okayama University Hospital
Ikeda, Tohru Department of Transfusion Medicine, Okayama University Hospital
Asano, Naomi Department of Transfusion Medicine, Okayama University Hospital
Ogo, Hiroaki Department of Transfusion Medicine, Okayama University Hospital
Yamakawa, Miwa Department of Nursing, Okayama University Hospital
Takagi, Naoe Department of Nursing, Okayama University Hospital
Otsuka, Fumio Department of Transfusion Medicine, Okayama University Hospital
Ikeda, Kazuma Department of Transfusion Medicine, Okayama University Hospital
Abstract
Studies examining risk factors associated with vasovagal reactions (VVRs) during autologous blood donations, especially in younger subjects, have been limited. The aim of the present study was to define risk factors for VVRs during preoperative autologous blood donation in patients, including those younger than 18 years old. We retrospectively analyzed 4192 autologous, preoperative blood donations between 2007 and 2015 at Okayama University Hospital. Eighty-seven (2.08%) of the patients experienced VVRs. VVRs occurred approximately three times as often in patients 0-17 years old (16/320, 5.0%) than in patients 18 years and older (71/3872, 1.8%). In particular, VVRs occurred more frequently in those 10-13 years old, and decreased with older age (P = 0.006). In a univariate analysis, younger age, lower body mass index, lower systolic blood pressure, lower body weight, lower total blood volume, female gender, first-time collection, and higher heart rate were associated with a higher incidence of VVRs. In a multivariate analysis, lower systolic blood pressure (P < 0.001), higher heart rate (P = 0.007), and first-time collection (P = 0.015), remained independent predictors of VVRs. These results emphasize the need for careful attention during blood collection.
Keywords
Autologous blood donation
Vasovagal reactions
Note
This is an Accepted Manuscript of an article published by Springer
Published Date
2017-06
Publication Title
International Journal of Hematology
Volume
volume105
Issue
issue6
Publisher
Elsevier Science
Start Page
812
End Page
818
ISSN
0925-5710
NCID
AA10797094
Content Type
Journal Article
language
英語
OAI-PMH Set
岡山大学
Copyright Holders
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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isVersionOf https://doi.org/10.1007/s12185-017-2204-6