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ID 32040
JaLCDOI
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Author
Inaba, Kozo
Doi, Akitaka
Nishida, Isamu
Abstract

A heat stable cell growth inhibiting factor was isolated from rat liver microsomes by hot salt extraction, ethanol fractionation and the hot phenol method. The factor was contained in the RNA fraction (designated as mhRNA). mhRNA inhibited the growth of mouse fibroblast (L-929) cells at a relatively low concentration (55 microgram/ml of culture medium). The molecular weight of mhRNA was about 27,000 and the base composition was guanine and cytosine rich.

Keywords
cell growth inhibitor
liver
microsomes
RNA
Amo Type
Article
Published Date
1979-08
Publication Title
Acta Medica Okayama
Volume
volume33
Issue
issue4
Publisher
Okayama University Medical School
Start Page
213
End Page
217
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
NAID