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ID 48272
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Author
Ghosh, S
Kobayashi, N
Nagashima, S
Chawla-Sarkar, M
Krishnan, T
Ganesh, B
Naik, TN
Abstract
Studies on bovine group B rotaviruses (GBRs) are limited. To date, only the VP6 gene of a single bovine GBR strain and the VP7 and NSP5 genes of a few bovine GBR strains have been sequenced and analyzed. In the present study, using a single-primer amplification method, we have determined the full-length nucleotide sequences of the VP1, VP2, VP4, VP6, NSP1 and NSP2 genes of three bovine GBR strains from eastern India. In all six of these genes, the bovine GBR strains shared high genetic relatedness among themselves but exhibited high genetic diversity with cognate genes of human, murine and ovine GBRs. Interestingly, as with group A rotaviruses, the bovine GBR VP1, VP2, VP6 and NSP2 genes appeared to be more conserved than the VP4 and NSP1 genes among strains of different species. The present study provides important insights into the genetic makeup and diversity of bovine GBRs, and also identifies a novel GBR VP4 genotype.
Published Date
2009-11-21
Publication Title
Archives of Virology
Volume
volume155
Issue
issue2
Publisher
Springer
Start Page
159
End Page
167
ISSN
0304-8608
NCID
AA00548901
Content Type
Journal Article
Project
Collaborative Research of Okayama University for Infectious Diseases in India
Official Url
http://www.springerlink.com/content/f24n7361k1370257/
language
英語
Copyright Holders
© Springer-Verlag 2009
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Refereed
True
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