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ID 51884
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Title Alternative
Genetically engineered oncolytic adenovirus induces autophagic cell death through an E2F1-microRNA-7-epidermal growth factor receptor axis
Author
Yano, Syuya
Yoshida, Ryosuke
Yamasaki, Yasumoto
Sasaki, Tsuyoshi
Hashimoto, Yuuri
Kuroda, Shinji
Ouchi, Masaaki
Onishi, Teppei
Uno, Futoshi
Urata, Yasuo
Keywords
アデノウイルス
テロメラーゼ
マイクロRNA
オートファジー
EGFR
Note
平成24年度岡山医学会賞がん研究奨励賞(林原賞・山田賞)(The 2012 Okayama Medical Association Awards)
Published Date
2013-12-02
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume125
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
195
End Page
199
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Related Url
http://www.okayama-u.ac.jp/user/oma/
References
1) Mizushima N, Komatsu M : Autophagy : renovation of cells and tissues. Cell (2011) 147, 728-741.
2) Sato K, Tsuchihara K, Fujii S, Sugiyama M, Goya T, Atomi Y, Ueno T, Ochiai A, Esumi H : Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res (2007) 67, 9677-9684.
3) Azad MB, Chen Y, Henson ES, Cizeau J, McMillan-Ward E, Israels SJ, Gibson SB : Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3. Autophagy (2008) 4, 195-204.
4) Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB : Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell (2005)120, 237-248.
5) Ito H, Aoki H, Kuhnel F, Kondo Y, Kubicka S, Wirth T, Iwado E, Iwamaru A, Fujiwara K, Hess KR, Lang FF, Sawaya R, et al. : Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus. J Natl Cancer Inst (2006) 98, 625-636.
6) Ulasov IV, Tyler MA, Zhu ZB, Han Y, He TC, Lesniak MS : Oncolytic adenoviral vectors which employ the surviving promoter induce glioma oncolysis via a process of beclin-dependent autophagy. Int J Oncol (2009) 34, 729-742.
7) Jiang H, Gomez-Manzano C, Aoki H, Alonso MM, Kondo S, McCormick F, Xu J, Kondo Y, Bekele BN, Colman H, Lang FF, Fueyo J : Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells : role of autophagic dell death. J Natl Cancer Inst (2007) 99, 1410-1414.
8) Si ML, Zhu S, Wu H, Lu Z, Wu F, Mo YY : miR-21-mediated tumor growth. Oncogene (2007) 26, 2799-2803.
9) Tazawa H, Tsuchiya N, Izumiya M, Nakagama H : Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci USA (2007) 104, 15472-15477.
10) Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, Shimizu M, Wojcik SE, Aqelian RI, Zupo S, Dono M, Rassenti L, Alder H, et al. : miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA (2005) 102, 13944-13949.
11) Tazawa H, Yano S, Yoshida R, Yamasaki Y, Sasaki T, Hashimoto Y, Kuroda S, Ouchi M, Onishi T, Uno F, Kagawa S, Urata Y, et al. : Genetically engineered oncolytic adenovirus induces autophagic cell death through an E2F1-microRNA-7-epidermal growth factor receptor axis. Int J Cancer (2012) 131, 2939-2950.
12) Liu D, Kojima T, Ouchi M, Kuroda S, Watanabe Y, Hashimoto Y, Onimatsu H, Urata Y, Fujiwara T : Preclinical evaluation of synergistic effect of telomerase-specific oncolytic virotherapy and gemcitabine for human lung cancer. Mol Cancer Ther (2009) 8, 980-987.
13) Webster RJ, Giles KM, Price KJ : Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J Biol Chem (2009) 284, 5731-5741.
language
日本語
Copyright Holders
Copyright (c) 2013 岡山医学会
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Refereed
True
DOI
Eprints Journal Name
joma