このエントリーをはてなブックマークに追加
ID 49378
FullText URL
Thumnail 125_9.pdf 3.15 MB
Title Alternative
Telomerase-specific virotherapy targeting lymph node micrometastasis of human cancer
Author
Kojima, Toru
Watanabe, Yuichi
Hashimoto, Yuuri
Kuroda, Shinji
Yamasaki, Yasumoto
Yano, Shuya
Uno, Futoshi
Tanaka, Noriaki
Urata, Yasuo
Keywords
telomerase
oncolytic adenovirus
lymph node metastasis
orthotopic colorectal cancer model
<i>Alu</i> sequence
Note
平成23年度岡山医学会賞(林原賞)受賞論文 (The 2011 Okayama Medical Association Award)
Published Date
2013-04-01
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume125
Issue
issue1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
9
End Page
12
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Related Url
http://www.okayama-u.ac.jp/user/oma/
References
1) Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW : Specific association of human telomerase activity with immortal cells and cancer. Science (1994) 266, 2011-2015.
2) Nakayama J, Tahara H, Tahara E, Saito M, Ito K, Nakamura H, Nakanishi T, Tahara E, Ide T, Ishikawa F : Telomerase activation by hTERT in human normal fibroblasts and hepatocellular carcinomas. Nat Genet (1998) 18, 65-68.
3) Kawashima T, Kagawa S, Kobayashi N, Shirakiya Y, Umeoka T, Teraishi F, Taki M, Kyo S, Tanaka N, Fujiwara T : Telomerase-specific replication-selective virotherapy for human cancer. Clin Cancer Res (2004) 10, 285-292.
4) Watanabe T, Hioki M, Fujiwara T, Nishizaki M, Kagawa S, Taki M, Kishimoto H, Endo Y, Urata Y, Tanaka N, Fujiwara T : Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells. Exp Cell Res (2006) 312, 256-265.
5) Fujiwara T, Kagawa S, Kishimoto H, Endo Y, Hioki M, Ikeda Y, Sakai R, Urata Y, Tanaka N, Fujiwara T : Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel : preclinical evaluation of chemovirotherapy. Int J Cancer (2006) 119, 432-440.
6) Umeoka T, Kawashima T, Kagawa S, Teraishi F, Taki M, Nishizaki M, Kyo S, Nagai K, Urata Y, Tanaka N, Fujiwara T : Visualization of intrathoracically disseminated solid tumors in mice with optical imaging by telomerase-specific amplification of a transferred green fluorescent protein gene. Cancer Res (2004) 64, 6259-6265.
7) Kojima T, Hashimoto Y, Watanabe Y, Kagawa S, Uno F, Kuroda S, Tazawa H, Kyo S, Mizuguchi H, Urata Y, Tanaka N, Fujiwara T : A simple biological imaging system for detecting viable human circulating tumor cells. J clin Invest (2009) 119, 3172-3181.
8) Kishimoto H, Kojima T, Watanabe Y, Kagawa S, Fujiwara T, Uno F, Teraishi F, Kyo S, Mizuguchi H, Hashimoto Y, Urata Y, Tanaka N, et al. : In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus. Nat Med (2006) 12, 1213-1219.
9) Kojima T, Watanabe Y, Hashimoto Y, Kuroda S, Yamasaki Y, Yano S, Ouchi M, Tazawa H, Uno F, Kagawa S, Kyo S, Mizuguchi H, et al. : In Vivo Biological Purging for Lymph Node Metastasis of Human Colorectal Cancer by Telomerase-Specific Oncolytic Virotherapy. Ann Surg (2010) 251, 1079-1086.
language
日本語
Copyright Holders
Copyright (c) 2013 岡山医学会
File Version
publisher
Refereed
True
DOI
Eprints Journal Name
joma