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Title Alternative
Frequent silencing of tumor-suppressive miR-34b/c by aberrant methylation in malignant pleural mesothelioma
Author
Kubo, Takafumi
Keywords
悪性胸膜中皮腫
マイクロRNA
miR-34
methylation
p53
Note
平成23年度岡山医学会賞(山田賞)受賞論文 (The 2011 Okayama Medical Association Award)
Published Date
2012-12-03
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume124
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
203
End Page
206
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Related Url
http://www.okayama-u.ac.jp/user/oma/
References
1) Spirtas R, Heineman EF, Bernstein L, Beebe GW, Keehn RJ, Stark A, Harlow BL, Benichou J : Malignant mesothelioma : attributable risk of asbestos exposure. Occup Environ Med (1994) 51, 804-811.
2) Robinson BW, Musk AW, Lake RA : Malignant mesothelioma. Lancet (2005) 366, 397-408.
3) Metcalf RA, Welsh JA, Bennett WP, Seddon MB, Lehman TA, Pelin K, Linnainmaa K, Tammilehto L, Mattson K, Gerwin BI : p53 and Kirsten-ras mutations in human mesothelioma cell lines. Cancer Res (1992) 52, 2610-2615.
4) Cote RJ, Jhanwar SC, Novick S, Pellicer A : Genetic alterations of the p53 gene are a feature of malignant mesotheliomas. Cancer Res (1991) 51, 5410-5416.
5) Shimamura A, Fisher DE : p53 in life and death. Clin Cancer Res (1996) 2, 435-440.
6) Bartel DP : MicroRNAs : genomics, biogenesis, mechanism, and function. Cell (2004) 116, 281-297.
7) Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, et al. : MicroRNA expression profiles classify human cancers. Nature (2005) 435, 834-838.
8) Garzon R, Calin GA, Croce CM : MicroRNAs in cancer. Annu Rev Med (2009) 60, 167-179.
9) He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, et al. : A microRNA component of the p53 tumour suppressor network. Nature (2007) 447, 1130-1134.
10) Hermeking H : p53 enters the microRNA world. Cancer Cell (2007) 12, 414-418.
11) Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T : Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res (2008) 68, 4123-4132.
12) Kubo T, Toyooka S, Tsukuda K, Sakaguchi M, Fukazawa T, Soh J, Asano H, Ueno T, Muraoka T, Yamamoto H, Nasu Y, Kishimoto T, et al. : Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma. Clin Cancer Res (2011) 15, 4965-4974.
language
日本語
Copyright Holders
Copyright (c) 2012 岡山医学会
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publisher
Refereed
True
DOI
Eprints Journal Name
joma