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ID 15160
JaLCDOI
Sort Key
14
Title Alternative
A case report of mixed connective tissue disease.
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Author
Takata, Ichiro
Kitani, Hikaru
Mifune, Takashi
Mitsunobu, Fumihiro Kaken ID researchmap
Kajimoto, Kazuhiro
Matsumura, Tadashi
Yokota, Satoshi
Tanizaki, Yoshiro
Abstract
症例は50歳女性で,1991年頃より両肘関節の疼痛とレイノー現象を自覚するようになり前医にて慢性関節リウマチ(Rheumatoid arthritis, 以下RAと略)との診断を受け加療受けるも症状の改善なく,当科を受診した。典型的な慢性関節リウマチの症状に乏しく,他の膠原病の存在を疑って検索したところ,抗RNP抗体陽性等の所見から,混合性結合組織病(mixed connective tissue disease, 以下MCTDと略)と診断した。MCTDは初診時に慢性関節リウマチと誤診される例が多く,慢性関節リウマチに非典型的な症状を伴う場合は,MCTDが鑑別診断として重要と考えられた。
Abstract Alternative
A 50-year-old woman, diagnosed as rheumatoid arthritis (RA) in 1991, had been treated with Lobenzarit disodium and non steroidal anti-inflammatory drugs (NSAIDs) before administration at our hospital. Despite the treatment with these drugs, her symptoms did not improve. She was admitted to our hospital for her progressive bilateral elbow joint pain and Raynaud's phenomenon. Although abnormal values of laboratory examinations such as an increased ESR (64mm/1hr), increased level of serum IgG (2854mg/㎗) and a positive RA test were shown, the clinical features of classical RA were not clear. There, she was diagnosed as mixed connective tissue disease (MCTD), because of high level of anti-RNP antibody in serum, Raynaud's phenomenom, multiple arthritis and constrictive ventilatory disturbance. Her symptoms and the results of labolatory examinations were clearly improved by glucocorticoid therapy.
Keywords
混合性結合組織病 (MCTD)
慢性関節リウマチ (Rheumatoid arthritis)
抗RNP抗体 (Anti-RNP antibody)
Publication Title
岡大三朝分院研究報告
Published Date
1994-09
Volume
volume65
Publisher
岡山大学医学部附属病院三朝分院
Publisher Alternative
Misasa Medical Branch, Okayama University Medical School
Start Page
96
End Page
100
ISSN
0918-7839
NCID
AN10430852
Content Type
Departmental Bulletin Paper
OAI-PMH Set
岡山大学
language
日本語
File Version
publisher
NAID
Eprints Journal Name
mmc