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ID 53744
Sort Key
8
Title Alternative
A case report of giant ectopic pheochromocytoma conversion therapy with radioisotope therapy and chemotherapy followed by curative resection
FullText URL
Thumnail 127_213.pdf 15.2 MB
Author
Yasui, Kazuya
Umeda, Yuzo
Kumano, Kenjiro
Tabata, Masahiro
Otsuka, Fumio
Yagi, Takahito
Fujiwara, Toshiyoshi
Abstract
A 46-year-old man was found to be positive for occult blood at a medical checkup and was revealed to have a 14-cm tumor on the right side of abdominal aorta by a subsequent abdominal CT scan. The endocrinology laboratory data showed elevations in the levels of serum noradrenaline, and ectopic pheochromocytoma was suspected. The tumor was compressing the inferior vena cava and portal vein, the superior mesenteric artery and the pancreas. Since it would be difficult to cure by operation, neoadjuvant therapy was started using radioisotope therapy by I-131 metaiodobenzylguanidine (131I-MIBG) and chemotherapy (CVD therapy ; cyclophosphamide, vincristine, dacarbazine). He was treated with three courses of radioisotope therapy and 16 courses of chemotherapy, which significantly reduced the tumor size. This made radical resection possible ; we were able to avoid the merger excision of great vessels and other organs. On pathological and immunopathological findings, the tumor was diagnosed as ectopic pheochromocytoma. Regarding the safety and curability of the treatment, neoadjuvant therapy may be useful in treating very large tumors that show invasion of other organs.
Keywords
異所性褐色細胞腫(ectopic pheochromocytoma)
化学療法(chemo therapy)
131I-MIBG
Note
症例報告(Case Reports)
Publication Title
岡山医学会雑誌
Published Date
2015-12-01
Volume
volume127
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
213
End Page
218
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Related Url
isVersionOf https://doi.org/10.4044/joma.127.213
OAI-PMH Set
岡山大学
language
日本語
Copyright Holders
Copyright (c) 2015 岡山医学会
File Version
publisher
Refereed
True
DOI
NAID
Eprints Journal Name
joma