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ID 18886
Eprint ID
18886
FullText URL
Thumnail 70_1161.pdf 4.66 MB
Title Alternative
The influence of the blocking of autonomic nerves upon the anaphylactic phenomenon. Part Ⅱ. The influences of the blocking of autonomic nerves by medicines upon the local anaphylactic phenomenon
Author
Kawata, Koichi
Abstract
The influences of Ravonal, Procaine, Promethazine and Chlorpromazine upon the local anaphylactic phenomenon on rabbits were investigated. 1. Ravonal anesthesia as well as general and local administration of Procaine have no influences upon the manifestation of the Arthus phenomenon. This is considered to be based on their temporary actions. 2. The general and local administration of Promethazine and Chlorpromazine showed the significant inhibition to the Arthus phenomenon and their effects were shown markedly by the administration of Chlorpromazine. This inhibitory effects are considered to be based on the antagonistic actions against the accentuation of vessel permeabilities through the autonomic nerves. 3. The influences of the anesthesia and artificial hibernation upon the aquiring of the anaphylaxy were investigated by the Arthus phenomenon and the precipitin value in blood and there were no significant differences against the control. This is considered to be based on the incomplete blocking of autonomic nervous function through over the antibody producing periods. 4. Ravonal anesthesia as well as general and local administration of Procaine showed a slight inhibition to the Shwartzman phenomenon. This is, also, considered to be caused by their temporary action, but the manifestation is much earlier than the Arthus phenomenon. 5. The general and local administration of Promethazine or Chlorpromazine showed significant inhibition to the Shwartzman phenomenon. This is considered to be based on the antagonistic action against the accentuation of vessel permeability through the antonomic nerves.
Published Date
1958-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume70
Issue
issue4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1161
End Page
1169
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/70/4/70_4_1161/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma