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ID 18885
Eprint ID
18885
FullText URL
Thumnail 70_1153.pdf 472 KB
Title Alternative
The influence of the blocking of autonomic nerves upon the anaphylactic phenomenon. Part 1. The influences of the blocking of autonomic nerves by medicines upon the general anaphylaxy
Author
Kawata, Koichi
Abstract
The influences of Ravonal, Procaine, Promethazine and Chlorpromazine upon the general anaphylaxy on rabbits were investigated. 1. Ravonal showed the definite inhibitory reaction upon the general anaphylaxy, which depended upon the depth of anesthesia. It did not show any marked effect in light anesthesia, while, in deep, it showed the prominent inhibitory effect. That is, the inhibitory effects varried markedly with the depth of the anesthesia. 2. As soon as the anesthetic effects reached to hypothalamus, the marked inhibitory effects were shown. This is considered to be caused by the mechanism based on the anesthetic effect on the autonomic nerve center. 3. Although Procaine showed an inhibitory reaction, the effects were slight. 4. Either Promethazine or Chlorpromazine showed the strong inhibitory reaction. 5. The excellent inhibitory effects of these phenothiazine derivatives upon the general anapylaxy are regarded to have much factors on central anesthetic reactions against the autonomic nerve system than their reactions against antihistamine and antiacetylcholine effects.
Published Date
1958-04-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume70
Issue
issue4
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1153
End Page
1160
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/70/4/70_4_1153/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma