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ID 40836
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Title Alternative
The Experimental Study on the Rat Thyroid Function by the Use of I(131) I. The Influence of Antithyroid, Thyroid Substance and Thyroid Stimulating Hormone on the Rat Thyroid
Author
Kawai, Keizo
Abstract
After the administration of antithyroid drug, thyroid substance or thyroid stimulating hormone, the weight, the uptake of Radioiodine and iodization in the rat thyroid gland were studied. The separation of the thyroxine from other iodine containing compounds of the thyroid gland were based on the method of Taurog, Chaikoff. The results obtained from the study are as follows: 1) The thyroid gland of rat in which hormonal synthesis was blocked by methiocil showed the secondary decrease of I131 uptake and compensatory hypertrophy and increase of weight by the T. S. H. 2) The administration of Thyreoidin produced the decrease of I(131) uptake and thyroid weight, and the atrophy of the thyroid gland. It's due to the depressing of hormonal synthesis and secretion in the thyroid gland in accordance with the decrease of T. S. H. It means the hypofunction of the thyroid gland. 3) The administration of T. S. H. produced an increase of I(131) uptake by the thyroid gland and an increaseof hormone secretion, showing hyperfunction of thyroid gland.
Published Date
1959-05-01
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume71
Issue
issue6-1
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
2783
End Page
2795
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/71/6-1/71_6-1_2783/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma