JaLCDOI 10.18926/21181
Title Alternative A case of SLE with non-erosive joint deformity -Jaccoud's type arthropathy-
FullText URL 048_043_048.pdf
Author Tanaka, Juntaro| Domyo, Michihiro| Takasugi, Kiyoshi| Irino, Shozo| Morinaga, Hiroshi|
Abstract A case of SLE in a twenty-eight year old woman, who had polyarthritis with non-erosive joint deformity, was reported. Differential diagnosis in this case included (1) rheumatoid arthritis (2) postrheumatic fever arthritis (Jaccoud's arthritis) and (3) the overlap syndrome between SLE and rheumatoid arthritis. Laboratory findings on this patient and review on literature, however, strongly suggested that this lady had been suffering from Jaccoud's type arthropathy of SLE. Corticosteroid therapy was initiated and the clinical course of the patient thereafter has been more than favorable.
Publication Title 岡山大学温泉研究所報告
Published Date 1979-03-25
Volume volume48
Start Page 43
End Page 48
ISSN 0369-7142
language 日本語
File Version publisher
NAID 40000321139
JaLCDOI 10.18926/40189
Title Alternative Medical studies on the rural people (3). Incidence rate of hypertension in rural districts, Tottori Prefecture, Japan
FullText URL pitsr_037_037_042.pdf
Author Inoue, Masakatsu| Morinaga, Hiroshi|
Abstract The authors examined the blood pressure levels of 5, 358 out-patients of Branch Hospital of Okayama University Hospital, Tottori Prefecture, during the four-year period, from April, 1957 to March, 1961. The following results were obtained: I. The incidence of hypertension with a systolic blood pressure over 150 mmHg was 20.5% (1,093 cases of 5,358). 2. Patients with hypertension over 40 years of age was 35.9% in male and 41.5% in female. Females showed a higher incidence than males and the incidence rate of hypertension increased with age. 3. There was a tendency in the incidence rate of patients with hypertension decreased in summer and increased in cold seasons.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 37
End Page 42
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002400930
JaLCDOI 10.18926/40332
Title Alternative MEDICAL STUDIES ON THE RURAL PEOPLE (II) A STUDY ON THE INCIDENCE OF STRUMA IN THE SOUTH-WESTERN RURAL DISTRICTS OF OKAYAMA PREFECTURE, JAPAN
FullText URL pitsr_014_051_056.pdf
Author Morinaga, Hiroshi|
Abstract The author investigated the thyroid glands of 1480 school children (aged from 6 to 14) living in the vicinity of Yakage, the south-western rural district of Okayama Prefecture, and 1516 out-patients of Yakage Hospital, in 1950. The incidence of struma among the school children was 4.6 per cent and among the out-patients 4.7% on an average, and the percentage of struma in the spring (7.8%) was higher than in the summer (2.98%). This result suggests that thyroid glands are in some way susceptible to seasonal influences, and it is therefore necessary to consider the effect of season during investigation. The white blood pictures of seven patients showed no specific findings.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 51
End Page 56
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002462907
JaLCDOI 10.18926/40331
Title Alternative MEDICAL STUDIES ON THE RURAL PEOPLE (I) CLINICAL AND STATISTICAL OBSERVATIONS ON HOOKWORM DISEASE IN RURAL DISTRICTS
FullText URL pitsr_014_045_050.pdf
Author Morinaga, Hiroshi|
Abstract The author studied statistically 160 cases of hookworm infection who had been admitted to Misasa Branch of Okayama University Hospital, Misasa Hot Springs in Tottori prefecture, during 1946~1949 and 162 cases of out-patients with anchylostomiasis in Yakage Hospital, Okayama Prefecture, during 1949~1950. The clinical findings were as follows: (1). Females showed a higher incidence than males and the incidence ratio of infected persons to total out-patients increased with age up to the 50~69 years group. (2). The most patients consulted our hospital for the first time in April~May and in August, and 62 per cent of cases came within 3 months scince they had noticed disorders in some way, but 22% remained at home without medical cure more than a year. (3). Chief subjective complaints were palpitation of heart (35.3%), lassitude of legs (31.2%), pains in the abdomen (22.9%), feeling of dizziness (21.6%) and so on. (4). Laboratory findings: The total number of erythrocytes was between 1.23 and 5.54 millions per cubic millimeter and a moderate anemia almost always developed in the hookworm disease (77.9% of all cases). The number of white cells was normal or slightly increased. Relative or absolute eosinophilia was recognized in 83.5% of all patients. Wassermann's test was positive in 20%, and Takata's reaction positive in 53% of the cases. The acidity of the gastric juice was lower than normal. Hypo- and anacidity were verified in 58%. Both albumen and urobilinogen test in urine were positive in 5.4% of 61 cases. Sugar in none. (5). Treatment: Thymol, tetrachlorethylene and oil of chenopodium were used alternately to remove the worms. The eggs in stool became negative after 3-4 times of the administration of anthelmintics in 76 per cent of 151 cases. As mentioned above, the patients infected with hookworm had various functional disorders of bodies, but they consulted the hospital only when the farmer's busy season began and their trouble became unbearable. And then the recovery of anemia took a month or two. Prof. Kitayama reported that the cold environment under 9°C. in the winter had perished the larva of hookworm in the soil. From these viewpoints, the author proposed that examination and cure of hookworms should be carried out in the winter, the slack season for farming, to prevent the fall of working ability due to anchylostomiasis during the busy farming seasons.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 45
End Page 50
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40330
language 日本語
File Version publisher
NAID 120002462906
JaLCDOI 10.18926/19662
Title Alternative Effect of aging on pancreatic exocrine function -Aging and fecal chymotrypsin activity-
FullText URL 057_024_028.pdf
Author Matsumoto, Shuji| Harada, Hideo| Ochi, Koji| Takeda, Masahiko| Tanaka, Juntaro| Morinaga, Hiroshi| Yoshida, Mitsuo| Kimura, Ikuro|
Abstract 膵外分泌機能に及ぼす加齢の影響を検討する目的で,健常人43名,非膵疾患患者41名,老人ホーム入居者39名を対象として比色法により糞便中キモトリプシン活性(FCA)を測定し,以下の結論を得た。1)FCAは逐齢的に低下し,60歳以上は60歳未満より有意の低値を示した。しかし,分布図のretrospectiveな検討からは,膵外分泌機能の低下は,実際には65~70歳あたりから明らかになることが示唆された。2)FCAの正常下限値を14.5U/gに定めたが,高齢者の診療にあたってはこの正常値のみを根拠にして疾病の有無を判定すべきではない。3)老人ホーム入居者のFCAは特に低値を取ったがその主要因は高齢者が多いためと考えられた。
Abstract Alternative To examine the effect of aging on the pancreatic exocrine function, fecal chymotrypsin activity (FCA) was measured by the photometric method in 43 healthy controls, 39 controls in an old-age home and 41 patients with non-pancreatic diseases. Following conclusions were obtained. 1) Pancreatic exocrine function showed a significant decrease with aging as indicated by the present prospective study : ① a significantly lower FCA in the B group of 22 healthy controls (≧ 60 years of age) than the A group of 21 healthy controls (< 60 years of ago) ; ② significant correlationship between aging and FCA in the 43 healthy controls and also in the 41 patients with non-pancreatic diseases. 2) FCA in controls in an old-age home was especially low. Presumably it was due to their far-advanced aging. 3) The calculated lower limit of normal in FCA was 14.5U/g. However, the diagnosis of pancreatic diseases should not be coined solely on the basis of decreased FCA value.
Keywords 糞便中キモトリプシン活性 (Fecal chymotrypsin activity) 加齢 (Aging) 膵外分泌機能 (Pancreatic exocrine function) 膵 (Pancreas) 酵素 (Enzyme)
Publication Title 環境病態研報告
Published Date 1986-07
Volume volume57
Start Page 24
End Page 28
ISSN 0913-3771
language 日本語
File Version publisher
NAID 120002309096
JaLCDOI 10.18926/40321
Title Alternative SEASONAL VARIATION OF GASTRIC ACIDITY
FullText URL pitsr_016_031_034.pdf
Author Morinaga, Hiroshi|
Abstract Since, in Japan situated in the temperate zone, climatic change through the four seasons of a year is regular, it is expected that there the physiological reactions of the human body may vary regularly in accordance with the climatic change. In fact, we experience that the attacks of diseases and their conditions are in close connection with the changes of the seasons. The author investigated the effect of the seasons upon the human gastric acidity, by means of the coffein-test, in 580 cases with gastrointestinal disorders, at the Misasa Branch Hospital of Okayama University, Misasa Spa in Tottori Prefecture, in 1946~1946. Hyperacidity was verified in 194 (33%) of 580 cases, normacidity in 134 (23%), anacidity in 138 (24%) and hypacidity in 114 (20%). The percentage of hyperacidity increases in winter (41%), decreases in spring (32%) and in summer (28%), and increases again in autumn (34%). The cases of anacidity decrease in winter and spring, but increase in summer. In chi-square test, the season and the acidity of gastric juice were taken as factors of variation. The chi-square was computed with the result: Pr {X(3)=14.013<16.919} =5%, so it cannot be asserted that the seasonal changes effect the acidity of gastric juice. But if Comparison is made between summer and winter with respect to the anacidity-hypacidity vs. the hyperacidity, the author: obtains Pr {X(2)=6.06> 5.412} =2%. It is thus verified that the cases of hyperacidity predominate over those of anacidity-hypacidity in winter, while the relation is reverse in summer. As was mentioned above, the tendency is obvious that the acidity of gastric juice decreases in summer and increases in winter. It was found that there is a regular seasonal variation in gastric acidity.
Publication Title 岡山大学温泉研究所報告
Published Date 1956-01
Volume volume16
Start Page 31
End Page 34
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40318
language 日本語
File Version publisher
NAID 120002462901
JaLCDOI 10.18926/40343
Title Alternative STUDIES ON VITRIOL SPRINGS (3) EFFECT OF THE INTERNAL USE OF VITRIOL WATER OF FUJINO ON THE GASTRIC ACIDITY
FullText URL pitsr_013_009_014.pdf
Author Morinaga, Hiroshi|
Abstract Fujino Spring is the foremost acid vitriol spring of Japan in ferrous and ferric ion contents. Six years ago the author reported that its internal use had an remarkable hemopoietic effect on hypochromic anemia and delayed the curve of alimentary hyperglycemia in rabbit. Twenty ml. of this vitriol water was diluted with plain water to two hundred ml. and was given to twenty one patients by stomach tube at 37°C. Gastric acidity of the patients was measured at 30 minutes intervals during the following 150 minutes after the administration of the water. In six cases of normal acidity no significant difference was proved between the effects of the mineral water and of caffein control (0.2g. in 200 ml.). In six cases of hyperacidity it seemed that the vitriol water decreased in the acidity curve compared with control. In nine patients of hypo- and anacidity both free and total acidity curve was elevated by the use of the mineral water compared with caffein control. The internal use of Fujino Spring in moderate dilution with plain water regulated the gastric acidity.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 9
End Page 14
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002484879
JaLCDOI 10.18926/40313
Title Alternative EFFECT OF INTERNAL USE OF THERMAL WATER OF YUMURA AND MUSASHI HOT SPRINGS UPON THE ALIMENTARY HYPERGLYCEMIA IN RABBITS
FullText URL pitsr_017_008_012.pdf
Author Morinaga, Hiroshi|
Abstract The author investigated the effect of the internal use of thermal water of Yumura (weak alkaline spring, Hyogo Prefecture) and Musashi (weak common salt spring, Fukuoka Prefecture) Springs upon the alimentary hyperglycemia in rabbits. Sixty ml. of spring water, and of plain water as control, with 10% glucose in solution was administered to rabbits by stomach tube, and the blood sugar level was determined before and 1/2, 1, 2 and 3 hours after the administration. In all cases, the thermal water was revealed to inhibit the alimentary hyperglycemia significantly by comparing the results obtained with the thermal water and those with the plain water control.
Publication Title 岡山大学温泉研究所報告
Published Date 1956-03
Volume volume17
Start Page 8
End Page 12
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002462898
JaLCDOI 10.18926/19625
Title Alternative STUDIES ON BALNEOTHERAPY OF DIABETES MELLITUS (Ⅱ). EFFECT OF INTERNAL USE OF GERO HOT SPRING ON THE ALIMENTARY HYPERGLYCEMIA IN ALLOXAN-DIABETIC RABBITS
FullText URL 015_048_052.pdf
Author Morinaga, Hiroshi|
Abstract The author investigated the effect of the internal use of the hot spring water of Gero (Gifu Prefecture, Japan), which contained Cl' 167 mg./L., HCO(3)' 66.0 mg./L. and titrated sulphur 0.6 mg./L. (pH: 6.2) at the time of this experiment, upon the alimentary hyperglycemia in alloxan-diabetic rabbits. 1. The author injected alloxan of 150 mg. per kg. of body weight intravenously into normal rabbits and performed the experiment 5~6 weeks after the injection. At the time of the experiment, the fasting blood sugar levels of alloxan-diabetic rabbits ranged from 107 to 211 mg./dl. (170 mg./dl. on the average). 2. Thirty ml. of 10% glucose solution in thermal water or in plain water per kg. of body weight was administered to the rabbits by stomach tube, and blood sugar level was determined before and 1/2, 1, 2, 3, 4 and 5 hours after the administration. The rejection interval (5%) of the glucose tolerance in 17 normal rabbits is shown in Fig. Ⅰ. Glucose tolerance curves of these alloxan-diabetic rabbits were out of the limit of the normal range. 3. Gero Hot Spring water had no inhibitory action upon the alimentary hyperglycemia of alloxan-diabetic rabbits.
Publication Title 岡山大学温泉研究所報告
Published Date 1955-03-25
Volume volume15
Start Page 48
End Page 52
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002309141
JaLCDOI 10.18926/19621
Title Alternative STUDIES ON BALNEOTHERAPY OF DIABETES MELLITUS (Ⅰ). EFFECT OF THE RADIOACTIVE THERMAL BATH UPON THE CARBOHYDRATE METABOLISM AND THE LEUCOCYTE PICTURE IN ALLOXAN-DIABETIC RABBITS.
FullText URL 015_034_047.pdf
Author Morinaga, Hiroshi|
Abstract The author investigated the effect of the radioactive thermal bath upon the carbohydrate metabolism and the leucocyte picture in alloxan-diabetic rabbits. 1. The author injected 100-200 mg. of alloxan per kg. of body weight intravenously into normal rabbits and produced alloxan diabetes. The triphasic blood sugar response to the injection of alloxan is illustrated in Table 1. and Fig. 1. About a week after the injection of alloxan, the fasting blood sugar values ranged 127 to 331 mg./dl. (Table 3.). 2. In this experiment the alloxan-diabetic rabbits were put in radioactive hot spring and plain water bath, 42-44℃. in temperature. The radioactive hot springs put in use are "Hisui-no-Yu" and "Kenkyusho-sen" (the Loboratory-Spring), both in Misasa Spa, the chemical compositions of which are given in Table 2. 3. In any case, the blood sugar level rose temporarily after the thermal baths for 5 minutes, but the 24-hour blood sugar value after taking a bath was lower in "Hisui-no-Yu" (Rn: 300-400 Mache units) than in "Kenkyusho-sen" (Rn: 10-30 Mache units) (Table 3 and Fig. 2). 4. The glucose tolerance was found to be abnormal in alloxan-diabetic rabbits even 3 months after the injection of alloxan, but this abnormal carbohydrate metabolism tended to become normal by the radioactive thermal bath (Table 5, 6 and Fig. 3, 5.). 5. The radioactive thermal bath in "Hisui-no-Yu" caused increase of leucocyte counts of alloxan-diabetic rabbits more remarkably than the bath in "Kenkyusho-sen" (Table 8. and Fig. 6).
Publication Title 岡山大学温泉研究所報告
Published Date 1955-03-25
Volume volume15
Start Page 34
End Page 47
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/21510
language 日本語
File Version publisher
NAID 120002314143
JaLCDOI 10.18926/40326
Title Alternative ASOZU (WEAK COMMON SALT SPRING), HAMAMURA (SULPHATED BITTER SPRING), KAlKE (CALCIUM CHLORIDE CONTAINING SALINE SPRING) AND FUJINO (ACID ALUM VITRIOL SPRING) SPRING WATERS AND THE ALIMENTARY HYPERGLYCEMIA
FullText URL pitsr_014_022_029.pdf
Author Morinaga, Hiroshi|
Abstract There are many experimental reports and clinical observations about the internal use of thermal waters on carbohydrate metabolism, and alkaline springs, alkaline common salt springs and sulphur springs are used for the balneological therapy of diabetic patients. The author reported that the internal use of the radon springs of Japan, such as Misasa, Ikeda and Masutomi thermal waters promoted the action of insuline and inhibited the experimental hyperglycemia in rabbits, and he suggested that these radioactive waters also would be able to utilize for the diabetic treatment. On the other hand, trace elements such as Cu, Zn and Mn have protective effects against disturbed carbohydrate metabolism of diabetic body. Some thermal waters contain these trace elements in various degrees, and Oshima & Ashizawa observed that after the drinking of Fujino mineral water the iron, copper, nickel and cobalt content in blood rose temporarily. In this report, the author investigated the influence of the drinking of Asozu (weak common salt spring), Hamamura (sulphated bitter spring), Kaike (calcium chloride containing saline spring) and Fujino (acid alum vitriol spring) Spring waters upon the alimentary hyperglycemia in rabbits. Thirty ml. of 10% glucose solution in thermal water (Fujino Water was diluted twice with plain water) or in plain water per kg. of bodyweight was administered to the rabbit by stomach tube and blood sugar level was determined before, 1/2, 1, 2, 3 and 4 hours after the administration. The results were as follows: 1. The drinking of Asozu Spring water inhibited the alimentary hyperglycemia compared with the plain water as a control. 2. Hamamura Spring had a tendency to decrease the blood sugar level. 3. Kaike Spring water had no inhibitory a.ction upon the alimentary hyperglycemia. 4. In spite of the existence of trace elements, Fujino mineral water had no significant effect. The author supposed that this was due to its high acidity.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 22
End Page 29
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002462903
JaLCDOI 10.18926/21313
Title Alternative Balneotherapy of gout
FullText URL pitsr_035_067_074.pdf
Author Morinaga, Hiroshi|
Publication Title 岡山大学温泉研究所報告
Published Date 1965-10-25
Volume volume35
Start Page 67
End Page 74
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002311030
Author Morinaga, Hiroshi|
Published Date 1965-10-25
Publication Title 岡山大学温泉研究所報告
Volume volume35
Content Type Others
JaLCDOI 10.18926/40142
Title Alternative A case of systemic lupus erythematosus with idiopathic thrombocytopenic purpura
FullText URL pitsr_042_025_029.pdf
Author Ichikawa, Yukinobu| Ikegami, Tadaoki| Kitayama, Minoru| Morinaga, Hiroshi|
Abstract A 24-year-old woman was presented in whom thrombocytopenic purpura appeared during antiinflammatory drugs therapy for arthralgia. At that time she had a positive LE cell preparation, positive antinuclear factor and false positive serum test for syphilis. Steroid hormon and ACTH therapy were started under the diagnosis of systemic lupus erythematosus. In the 23-rd hospital days, she had a negative LE cell preparation, negative antinuclear factor and negative serum test for syphilis. In the 28-th days after stopping steroid hormon and ACTH therapy, positive LE cell preparation and positive antinuclear factor appeared again.
Publication Title 岡山大学温泉研究所報告
Published Date 1973-03-25
Volume volume42
Start Page 25
End Page 29
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002398146
JaLCDOI 10.18926/21179
Title Alternative Studies on sinter deposit Misasa radioactive hot springs
FullText URL pitsr_048_025_033.pdf
Author Furuno, Katsushi| Tetsumoto, Junko| Aoki, Hiroko| Mifune, Masaaki| Morinaga, Hiroshi| Fukushima, Satoru| Wada, Hiroaki|
Abstract Sinter deposit in a distributing pipe used for about fifteen years in Misasa radioactive hot springs was investigated. The results were as follows; 1. The metal elements in this deposit were quaIi. tatively analysed by spectraspan plasma emission spectrophotometry (SPES), by fluorescent X-ray spectrometry, and following elements were detected; B, Na, Mg, AI, K, Ca, Mn, Fe, Cu, Zn, As, Sr, Ba and Pb. 2. The metal elements in this deposit were quantatively analysed by SPES and atomic absorption spectrophotometry, and following elements were determined; Fe : 508.7, As: 26.40, Ca: 7.85, Mn : 2.00, Al : 1.80, Na: 1.60, Zn: 1.33, K: 0.80, Cu: 0.67, Sr: 0.47, Mg: 0.35, Ba: 0.33 and B : 0.30 mg per gram. The color of this deposit was red brown, and the main component was ferric oxide. 3. Radioactive elements in this deposit were detected by autoradiography and radioluxography. Among the radioactive elements, concentration of radium was 320.5×10(-12)g/g (313.0×10(-12)Ci/g).
Publication Title 岡山大学温泉研究所報告
Published Date 1979-03-25
Volume volume48
Start Page 25
End Page 33
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002310949
JaLCDOI 10.18926/21103
Title Alternative Effects of swimming training in the hot spring pool on ventilatory function in bronchial asthma
FullText URL pitsr_054_013_018.pdf
Author Sudo, Michiyasu| Komagoe, Haruki| Okada, Chiharu| Nakago, Jitsuo| Tanizaki, Yoshiro| Morinaga, Hiroshi|
Abstract Effect of free swimming training in the hot spring pool (30℃) on ventilatory function were observed in nine patients with intractable asthma by measuring FVC, FEV(1.0), PEFR, MMF, V(50), V(25). 1. Swimming in the hot spring pool for three months allowed the reduction of glucocorticoid used for their asthma attack. 2. Although FVC was not affected by swimming training, EEV(1.0), PEFR, MMF, V(50), V(25) which represent obstructive ventilatory function were gradually improved by swimming training. The results show that free swimming training in the hot springpool is clinically available in intractable asthma.
Publication Title 岡山大学温泉研究所報告
Published Date 1984-03-25
Volume volume54
Start Page 13
End Page 18
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002310964
JaLCDOI 10.18926/19678
Title Alternative Spa therapy for bronchial asthma. Annual changes of characteristics of asthmatics admitted during the past four years.
FullText URL 057_037_041.pdf
Author Tanizaki, Yoshiro| Sudo, Michiyasu| Komagoe, Haruki| Morinaga, Hiroshi|
Abstract 1982年1月から1985年12月までの4年間に三朝分院内科へ入院し,温泉療法を受けた気管支喘息45例を対象にその年次推移を検討した。1.性別:初期2年間は男性の入院症例が多い状況であったが,後期2年間では男女比はほぼ等しかった。2.年令:年次推移はみられず,その平均年令は50±2才の間にあった。3.地域分布:初期2年間は岡山県からの入院症例が多数をしめたが,後期2年間ではむしろ鳥取県からの入院症例が増加する傾向がみられた。4.入院期間:初期2年間の平均入院期間は6.7カ月,6.5カ月とかなり長くなる傾向がみられたが,後期2年間ではそれぞれ3.0カ月,1.5カ月と明らかな短縮傾向がみられた。5.臨床病型:いずれの年度においても重症化傾向の強いⅠb型,Ⅱ型が多くみられたが,各年度間には差はみられなかった。6.ステロイド剤使用状況:年度の経過とともにその使用量は減少して いく傾向が示された。
Abstract Alternative Annual changes of characteristics, sex, area (Prefecture) of patients' coming from, term of admission, clinical classification of asthma and use of glucocorticoids, were examined in 45 patients with bronchial asthma who were admitted at Misasa Hospital, Okayama University Medical School and received spa therapy during the past four years from 1982 to 1985. In the first two years from 1982 to 1983, more patients with bronchial asthma were admitted from Okayama Prefecture, and the majority of them had severe asthma attacks and were more dependent on steroid-therapy. On the other hand, in the past two years from 1984 to 1985, number of patients with bronchial asthma from Tottori Prefecture increases, and their attacks were less severe and less dependent on steroid-therapy compared to the patients admitted during the first two years. Term of admission became shorter in the past two years than in the first two years. Any differences between the first and the past two years were not shown in sex, patient age and asthma types classified by clinical symptoms.
Keywords 気管支喘息 (Bronchial asthma) 温泉療法 (spa therapy) 臨床病型 (asthma type)
Publication Title 環境病態研報告
Published Date 1986-07
Volume volume57
Start Page 37
End Page 41
ISSN 09133771
language 日本語
File Version publisher
NAID 120002309135
JaLCDOI 10.18926/21121
Title Alternative Clinical problems of long-term steroid regimen for bronchial asthma, with reference to steroid-dependent cases
FullText URL pitsr_053_045_049.pdf
Author Komagoe, Haruki| Sudo, Michiyasu| Okada, Chiharu| Tanizaki, Yoshiro| Morinaga, Hiroshi| Kitani, Hikaru| Goda, Yoshinori| Tada, Shinya| Takahashi, Kiyoshi| Kimura, Ikuro|
Abstract Adverse side effects of steroid therapy were investigated in 32 asthmatic patients. Thirty-two patients were classified into three groups according to steroid therapy for the past five years; group 1 has been treated with continuous steroid therapy, group 2 with occasional steroid therapy and group 3 without steroid therapy. The results were as follows. 1. Group 1 showed a low level of serum cortisol at 8-9 a. m. The serum concentration of cortisol in patients with daily steroid regimen was lower as compared to that in patients with alternateday steroid therapy. 2. The daily profile of serum cortisol was low in the steroid dependent asthmatic patients, and little increase of serum cortisol level after the administration of prednisolone was shown in group 1. 3. Serum IgG and IgM levels were significantly low in steroid dependent asthmatic patients. 4. The level of serum potassium was low in group 1.
Publication Title 岡山大学温泉研究所報告
Published Date 1983-03-25
Volume volume53
Start Page 45
End Page 49
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002311040
Author Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Nakago, Jitsuo| Morinaga, Hiroshi| Ohtani, Jun| Tada, Shinya| Takahashi, Kiyoshi| Kimura, Ikuro|
Published Date 1984-04-30
Publication Title 岡山医学会雑誌
Volume volume96
Issue issue3-4
Content Type Journal Article
JaLCDOI 10.18926/21122
Title Alternative Clinical problems of long-term steroid regimen for bronchial asthma, with reference to steroid-dependent cases
FullText URL pitsr_053_051_055.pdf
Author Sudo, Michiyasu| Komagoe, Haruki| Murashima, Makoto| Okada, Chiharu| Tanisaki, Yoshiro| Morinaga, Hiroshi| Shiota, Yutaro| Kimura, Ikuro|
Abstract Adverse side effects of steroid therapy were investigated in 32 asthmatic patients. Thirty-two patients were classified into three groups according to steroid therapy for the past five years; group 1 has been treated with continuous steroid therapy, group 2 with occasional steroid therapy and group 3 without steroid therapy. The results were as follows. 1. Group 1 showed a low level of serum cortisol at 8-9 a. m. The serum concentration of cortisol in patients with daily steroid regimen was lower as compared to that in patients with alternateday steroid therapy. 2. The daily profile of serum cortisol was low in the steroid dependent asthmatic patients, and little increase of serum cortisol level after the administration of prednisolone was shown in group 1. 3. Serum IgG and IgM levels were significantly low in steroid dependent asthmatic patients. 4. The level of serum potassium was low in group 1.
Publication Title 岡山大学温泉研究所報告
Published Date 1983-03-25
Volume volume53
Start Page 51
End Page 55
ISSN 0369-7142
language 日本語
File Version publisher
NAID 120002310967