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ID 14110
Eprint ID
14110
FullText URL
Thumnail 105_559.pdf 192 KB
Title Alternative
Clinical evaluation of MAST System in the measurement of specific IgE in asthmatics
Author
Kitani, Hikaru
Mifune, Takashi
Kajimoto, Kazuhiro
Sugimoto, Keisuke
Yokota, Satoshi
Hiramatsu, Junichi
Kawaraya, Masashi
Tanizaki, Yoshiro
Abstract
The commercially available radioallergosorbent test (RAST) is still widely used as a good diagnostic tool for diagnosis of allergic diseases. Recently, a new in vitro test (Pharmacia CAP System and MAST Immunosystems MAST System) was proposed to measure IgE antibodies in a quantitive manner. The MAST System is based on cellulose fiber in a sort of pipette. The carrier can bind many kinds of allergens in the CNBr (cyanogen bromide) activated form, compared to the RAST paper disc. In this study, we examined serum levels of specific IgE antibodies to food allergens and inhalant allergens in forty bronchial asthma patients using the MAST System. Higher positivities of specific IgE antibodies were found in inhaled allergens than in food allergens. Although high positivities of specific IgE antibodies against food allergens did not correlate to patient age or age at onset, positive reaction to inhaled allergens in the MAST System was frequently observed in patients under the age of 40 or in those under age 30 at onset. The MAST System, which can measure specific IgE antibodies against sixteen different allergens with a single sample, is suggested to identify a larger number of atopic patients than RAST.
Keywords
気管支喘息
MAST システム
特異的 IgE
Published Date
1993
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume105
Issue
issue5-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
559
End Page
562
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/105/5-6/105_5-6_559/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma