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ID 32190
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Author
Hatano, Atsushi
Yamada, Masao Kaken ID researchmap
Uno, Fumio
Nii, Shiro
Abstract

Ability of two neurovirulent strains (F and +GC (LPV) Miyama) of herpes simplex virus type 1 (HSV-1) to establish and maintain reactivatable latency in trigeminal ganglia (TG) was compared after intranasal inoculation of mice. The +GC (LPV) Miyama strain showed a very low rate of virus reactivation in explant cultures of TG, while the F strain showed a high rate of reactivation. These data indicate that neurovirulent strains of HSV-1 are not always competent for reactivatable latency, although most virulent strains of HSV-1 thus far reported were competent for reactivatable latency.</P>

Keywords
herpes simplex virus type 1
neurovirulence
latency
reactivation
Amo Type
Article
Published Date
1991-04
Publication Title
Acta Medica Okayama
Volume
volume45
Issue
issue2
Publisher
Okayama University Medical School
Start Page
117
End Page
121
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT