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ID 13962
Eprint ID
13962
FullText URL
Thumnail 120_265.pdf 536 KB
Title Alternative
Epidermal growth factor receptor mutation status and adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung
Author
Suehisa, Hiroshi
Hotta, Katsuyuki
Uchida, Akiko
Fujiwara, Yoshiro
Matsuo, Keitaro
Takata, Minoru
Date, Hiroshi
Keywords
non-small cell lung cancer
adjuvant chemotherapy
uracil-tegafur
EGFR
Note
平成19年度岡山医学会賞(林原賞)受賞論文
Published Date
2008-12-01
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume120
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
265
End Page
269
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
References
1) Kato H, Ichinose Y, Ohta M, Hata E, Tsubota N, Tada H, Wadanabe Y, Wada H, Tsuboi M, Hamajima N, Ohta M : A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung. N Engl J Med (2004) 350, 1713-1721.
2) Olaussen KA, Dunant A, Fouret P, Brambilla E, André F, Haddad V, Taranchon E, Filipits M, Pirker R, Popper H, Stahel R, Sabatier L, et al. : DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med (2006) 355, 983-991.
3) Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, et al. : Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med (2004) 350, 2129-2139.
4) Mitsudomi T, Kosaka T, Endoh H, Horio Y, Hida T, Mori S, Hatooka S, Shinoda M, Takahashi T, Yatabe Y : Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol (2005) 23, 2513-2520.
5) Shigematsu H, Lin L, Takahashi T, Nomura M, Suzuki M, Wistuba II, Fong KM, Lee H, Toyooka S, Shimizu N, Fujisawa T, Feng Z, et al. : Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst (2005) 97, 339-346.
6) Ueda M, Kitaura K, Kusada O, Mochizuki Y, Yamada N, Terai Y, Kumagai K, Ueki K, Ueki M : Regulation of dihydropyrimidine dehydrogenase and pyrimidine nucleoside phosphorylase activities by growth factors and subsequent effects on 5-fluorouracil sensitivity in tumor cells. Jpn J Cancer Res (2000) 91, 1185-1191.
7) Magné N, Fischel JL, Dubreuil A, Formento P, Ciccolini J, Formento JL, Tiffon C, Renée N, Marchetti S, Etienne MC, Milano G : ZD1839 (Iressa) modifies the activity of key enzymes linked to fluoropyrimidine activity : rational basis for a new combination therapy with capecitabine. Clin Cancer Res (2003) 9, 4735-4742.
8) Suehisa H, Toyooka S, Hotta K, Uchida A, Soh J, Fujiwara Y, Matsuo K, Ouchida M, Takata M, Kiura K, Date H : EGFR Mutation Status and Adjuvant Chemotherapy with Uracil-Tegafur for Adenocarcinoma of the Lung. J Clin Oncol (2007) 25, 3952-3957.
9) Sordella R, Bell DW, Haber DA, Settleman J : Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science (2004) 305, 1163-1167.
10) Oki E, Sakaguchi Y, Toh Y, Oda S, Maehara Y, Yamamoto N, Sugimachi K : Induction of apoptosis in human tumour xenografts after oral administration of uracil and tegafur to nude mice bearing tumours. Br J Cancer (1998) 78, 625-630.
11) Tanaka F, Otake Y, Yanagihara K, Yamada T, Miyahara R, Kawano Y, Li M, Inui K, Wada H : Apoptosis and p53 status predict the efficacy of postoperative administration of UFT in non-small cell lung cancer. Br J Cancer (2001) 84, 263-269.
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
DOI
Eprints Journal Name
joma