このエントリーをはてなブックマークに追加
ID 18870
Eprint ID
18870
FullText URL
Thumnail 70_1019.pdf 3.52 MB
Title Alternative
Experimental Studies on the Pathogenesis of Polyradiculoneuritis Ⅰ. The Feature of Interactions With Coxsackie Group of Virus
Author
Ando, Osamu
Abstract
(1) The search was made to differentiate the possibilities of inducing the neuroallergy by infection in the case of polyradiculoneuritis with viruses of coxsackie group, strain Okumoto (A-2), Dohi (A-19) and Saragai (B-1) which were isolated from the patients with the polyradiculoneuritis showing Guillain-Barre Syndrome. (2) (A) Previous repeated administration of these three strains of coxsackie virus in the adult mice through intraperitoneal route and the challenge of identical virus intrathecally. (B) Similar repeated administration of PD(50) of poliovirus (Mahoney or Lansing strain) through intrathecal route and the challenge of coxsackie virus Okumoto Strain through same route to survived and sensitized mice after previous inoculations. The observation for 1 month revealed no significant signs of paralysis. Histologically no discernible picture of polyradiculoneuritis in the spinal root, ganglia, nerve and the ischias was clarified. (3) No acceptable evidence of the presence of neuroallergy by infection experimentally made in the above strains was obtained through the trials with coxsackie virus and polio virus in the mode of repeated inoculations.
Published Date
1958-03-31
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume70
Issue
issue3
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
1019
End Page
1035
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/70/3/70_3_1019/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma