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ID 13665
Eprint ID
13665
FullText URL
Thumnail 109_35.pdf 2.52 MB
Title Alternative
Histopathological study on choroidal vasculature in spontaneously hypertensive rats 2. Changes in the choroid and retinal pigment epithelial cells in the late stage of hypertension in these rats
Author
Sakaguchi, Noriko
Abstract
The pathological changes in the choroid and the retinal pigment epithelium in spontaneously hypertensive rats (SHR) aged 42-117 weeks were observed by transmission electron microscopy. Wistar Kyoto rats (WKY) were also studied as normotensive controls. Some of the endothelial cells of the choroidal arterioles and capillaries were degenerated. Focal cytoplasmic necrosis of the arteriolar smooth muscle cells was seen. The choroid showed severe sclerotic changes, and the retinal pigment epithelium was degeneated with dilated basal infoldings and intracellular vacuoles. Long-term hypertension causes degeneration of the outer retinal layer due to the obstructive changes in the choroidal vasculature.
Keywords
高血圧
脈絡膜
網膜
病理
Note
原著
Published Date
1997-06-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume109
Issue
issue3-6
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
35
End Page
40
ISSN
00301558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/109/3-6/109_3-6_35/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma