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ID 15849
Eprint ID
15849
FullText URL
Thumnail 100_37.pdf 650 KB
Title Alternative
Studies of lipid metabolism in cultured smooth muscle cells.Part I. Effect of antioxidants on cell proliferation and lipid peroxide formation.
Author
Demiya, Michitaka
Abstract
The effects of antioxidants on cell proliferation and lipid peroxide formation of cultured aortic smooth muscle cells obtained from normal, hypercholesterolemic and aged rabbits were studied in vitro.α-Tocopherol and coenzyme Q(10) were used as antioxidants.The lipid peroxide content of cells was generated in a time dependent manner with cell proliferation, it remained within the cells and did not accumulate in the media.α-Tocopherol promoted cell proliferation and suppressed the intracellular lipid peroxide formation expressed in terms of DNA content.These effects were significant only in HL-SMC, and were not significant in NR-SMC or Aged-SMC. Coenzyme Q(10) did not effect cell proliferation or lipid peroxide formation.
Keywords
平滑筋細胞
過酸化脂質
α-トコフェロール
コエンザイムQ(10)
抗酸化剤
Published Date
1988
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume100
Issue
issue1-2
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
37
End Page
45
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/100/1-2/100_1-2_37/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/index.html
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma