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ID 18892
Eprint ID
18892
FullText URL
Thumnail 73_687.pdf 17.2 MB
Title Alternative
Effects of β-Hydroxyglutamic Acid (β-OH-GA) on the Metabolism of the Perfused Cat Brain.
Author
Marukawa, Shoichi
Abstract
The perfusion of the cat brain was performed according to the method of Ikeda, H. who modified the method of Geiger, A.. Electrocorticographical, biochemical and pharmacological findings in the case of the administration of β-OHGA were obtained, and then the correlation of their appearances were investigated. 1). Electrocorticogram of the perfused cat brain was activated by the administration of β-OH-GA. 2). Following the activation of electrocorticogram, all reflexes as conjuctival, corneal reflexes, pupillary reactions and pain sensation were activated, and then spontanous body movement appeared at the same time. 3). Cerebral blood flow rate, oxygen and glcose consumption, lactic acid liberation were all increased. 4). The changes as above were reversible and soon recovered again by the perfusion without β-OH-GA. 5). Electrocorticogram and respiration rate did not showed any alteration. And, changes of blood pressure showed different case by case and represented not determinated tendency. 6). Any significant difference between effects of threo-type and erythro-type of β-OH-GA on the perfused cat brain was not observed.
Published Date
1961-09-30
Publication Title
岡山医学会雑誌
Publication Title Alternative
Journal of Okayama Medical Association
Volume
volume73
Issue
issue7-9
Publisher
岡山医学会
Publisher Alternative
Okayama Medical Association
Start Page
687
End Page
696
ISSN
0030-1558
NCID
AN00032489
Content Type
Journal Article
Official Url
https://www.jstage.jst.go.jp/article/joma1947/73/7-9/73_7-9_687/_article/-char/ja/
Related Url
http://www.okayama-u.ac.jp/user/oma/
language
日本語
Copyright Holders
岡山医学会
File Version
publisher
Refereed
True
Eprints Journal Name
joma