Proceedings of Okayama Association for Laboratory Animal Science
Published by Okayama Association for Laboratory Animal Science

<Availability>
Some items are not available because of decision by its author or publisher.

カフェインによるアレルギー性鼻炎の抑制効果

Tsujimoto, Madoka Graduate School of Human Life Sciences, Department of Foods and Human Nutrition, Notre Dame Seishin University
Saiki, Akiko Graduate School of Human Life Sciences, Department of Foods and Human Nutrition, Notre Dame Seishin University
Suzuki, Manami Graduate School of Human Life Sciences, Department of Foods and Human Nutrition, Notre Dame Seishin University
Shiraga, Toshiyuki Graduate School of Human Life Sciences, Department of Foods and Human Nutrition, Notre Dame Seishin University
Sugimoto, Yukio Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Hayashi, Yasushi Graduate School of Human Life Sciences, Department of Foods and Human Nutrition, Notre Dame Seishin University
Abstract
We examined the effects of caffeine treatment on ovalbumin- and histamine-induced rhinitis mouse models and on corticosterone and catecholamine levels in mouse plasma. Treatment with caffeine decreased sneezing and nasal rubbing in both models, but direct nasal administration had no effect. Plasma levels of corticosterone and catecholamine, which have known anti-allergy effects, were increased by caffeine treatment. The increases in corticosterone and catecholamine may be associated with the suppression of rhinitis symptoms.
Note
寄稿(Contribution)