Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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Complex spa therapy and airway inflammation in bronchial asthma

Tanizaki, Yoshiro
Kitani, Hikaru
Mifune, Takashi
Kajimoto, Kazuhiro
Yokota, Satoshi
Takata, Ichiro
Ochi, Koji
Harada, Hideo
Tada, Shinya
Harada, Mine
Abstract
Efficacy of complex spa therapy was studied in 55 patients with bronchial asthma. Complex spa therapy was effective in 47 (85.5%) of the 55 patients with bronchial asthma : marked efficacy was observed in 15 (27.3%), moderate in 32 (58.2%), slight in 6 (10.9%) and no efficacy in 2 patients (3.6%). Improvement of clinical symptoms and findings by complex spa therapy was more clearly observed in patients with an increased proportion of BAL lymphocytes, neutrophils and eosinophils. These findings suggest that complex spa therapy more affects cell infiltration in the airways than bronchoconstriction induced by chemical mediators. Improvement of ventilatory function represented by FEV1.0% value was higher in patients with a low proportion of BAL neutrophils, suggesting that patients with increased number of BAL neutrophils require longer complex spa therapy than those without BAL neutrophilia.
Keywords
complex spa therapy (複合温泉療法)
airway inflammation (気道炎症反応)
bronchial asthma (気管支喘息)
ISSN
0918-7839
NCID
AN10430852