Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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糖尿病の温泉治療に関する研究 Ⅱ.アロキサン糖尿家兎の食餌性過血糖と下呂溫泉(単純硫化水素泉)の飲用

Morinaga, Hiroshi
The author investigated the effect of the internal use of the hot spring water of Gero (Gifu Prefecture, Japan), which contained Cl' 167 mg./L., HCO(3)' 66.0 mg./L. and titrated sulphur 0.6 mg./L. (pH: 6.2) at the time of this experiment, upon the alimentary hyperglycemia in alloxan-diabetic rabbits. 1. The author injected alloxan of 150 mg. per kg. of body weight intravenously into normal rabbits and performed the experiment 5~6 weeks after the injection. At the time of the experiment, the fasting blood sugar levels of alloxan-diabetic rabbits ranged from 107 to 211 mg./dl. (170 mg./dl. on the average). 2. Thirty ml. of 10% glucose solution in thermal water or in plain water per kg. of body weight was administered to the rabbits by stomach tube, and blood sugar level was determined before and 1/2, 1, 2, 3, 4 and 5 hours after the administration. The rejection interval (5%) of the glucose tolerance in 17 normal rabbits is shown in Fig. Ⅰ. Glucose tolerance curves of these alloxan-diabetic rabbits were out of the limit of the normal range. 3. Gero Hot Spring water had no inhibitory action upon the alimentary hyperglycemia of alloxan-diabetic rabbits.