Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

芳香族有機溶剤の生体内運命 第二編 トルエン及びm-キシレン投与ラットの尿中代謝産物に対する四塩化炭素の影響

Kamiya, Jiroh
99_1641.pdf 257 KB
Abstract
The effect of carbon tetrachloride on the excretion of HA and m-MHA, metabolites of toluene and m-xylene, respectively, was examined. Urine was collected before the injection and 24, 48 and 72 hours after the injection and analysed for HA or m-MHA by HPLC. Total excretion of HA in the urine of rats injected with toluene and carbon tetrachloride (subcutaneously) was less than when toluene alone was injected. The more carbon tetrachloride was injected the less was the total excretion of HA in the urine. Total excretion of m-MHA in the urine of rats injected with m-xylene and carbon tetrachloride (subcutaneously) was less than when m-xylene alone was injected.
Keywords
四塩化炭素
高速液体クロマトグラフ
トルエン
m-キシレン
ISSN
0030-1558
NCID
AN00032489