Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

酵素処理によるラット腎糸球体基底膜の微細構造の観察

Ichiyasu, Akira
Takaoka, Michio
Takahashi, Kayo
Ota, Zenske
Thumnail 98_1111.pdf 681 KB
Abstract
Although various hypotheses have been proposed about the ultrastructure of the glomerular basement membrane (GBM) of the kidney, it has not clearly revealed. At present, it is thought to be composed of a meshwork of fibrils as reported by Ota et al. We successfully observed the meshwork structure of the GBM under an electron microscope after enzymatic treatment with α-amylase and elastase. The fibrils were about 30nm in width and were thought to be composed of type Ⅳ collagen.
Keywords
glomerular basement membrane
enzymatic digestion
ultrastructure
type Ⅳ collagen
ISSN
0030-1558
NCID
AN00032489