Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

低カタラーゼ血液症および無カタラーゼ血液症の蛍光抗体法による研究およびヘモグロビン酸化に関する研究 第2編 Choleglobin生成とカタラーゼ量について―特に正常血,低カタラーゼ血,無カタラーゼ血を中心に―

Seto, Takashi
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The oxidation of hemoglobin with ascorbic acid gives formation to choleglobin. In these reaction processes, catalase decomposes H(2)O(2) and inhibits choleglobin formation. In this experiment, we compared the degree of hemoglobin oxidation in human acatalasemic blood to that in human hypocatalsemic and normal blood. Results obtained were as follows: Choleheme increased with decrease in protoheme at the initial stage. After a certain time of the reaction, however, the formation of choleheme remained stationary and the formation of choleglobin was lower in the hypocatalasemic blood than the acatalasemic blood and in the case of the normal blood it was the lowest.