Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

保存血大量輸血に伴う血液凝固障害に関する研究 第2編 血液凝固障害発生の予防とその治療について

Shimizu, Hiroshi
For the impaired blood clotting due to massive blood transfusion prophylaxis is to be the best treatment, for measures after its occurreance are often very difficult. As prophylactic treatment, continuous drip infusion of a large amount of hydrocortisone, alternated transfusion of fresh and preserved blood, administration of tissue thromboplastin preparation and ACTH were effective. As thrapy for hemorrhagic tendency, massive infusion of hydrocortisone, administration of tissue thromboplastin preparation, transions of fressh blood or platelets were proved to be effective. For decreased clotting factors in case fibrinolysis. intravenous ε-aminocapronic acid and hydrocortisone were efficacious to depress the fibrinolysis.