Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

子宮癌に於ける子宮膣部の炎症像とその予後との関連性に就いて 第1編 子宮腟部に於ける炎症像とその予後との関連性に就いて

Fukai, Junichi
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So far it appears that cancer researches were mainly focused only on the parenchyma and the study on its stromal tissue was somewhat neglected. However, in 1949 Imai stated that the stromal reaction is closely associated with the prognosis in his report on C. P. L. classification and he emphasized that anti-earcinomataus factor exists in the stromal tissue of cancer. Being greatly attracted by his theory, the author studied inflammatory picture in uterine cancer and at the same time pursued the relationship between the inflammation and its prognosis. The materials used in the present investigation were specimens obtained from 902 cases of cervical cancer, treated in the Dept. of Obstetrics and Gynecology, Okayama University Medical Shcool during 12-year period from 1938 to 1949. As the results the author arrived at the following conclusions. 1. In both those given surgical treatment and those given radiation treatment, the prognosis is better in those showing a stronger inflammation in stroma than in those showing a weaker one. 2. However, only the case at the stage-IV cancer (rediation treatment) is an exception to this rule. 3. As for the relationship between Nagase's classification and the degree of inflammation, there can be recognized no great difference in the incidence of strong inflammation between type-I (58%) and type-II (55%), but the incidence of strong inflammation is least in type-III (28%). 4. The incidence of strong inflammation is greatest in the stage-II cancer (55%), followed by the stage-III cancer (46%), stage-I cancer (43%). and stage-IV cancer (42%) in the order mentioned.