Experimental Studies on Ligation of Inferior Vena Cava. Ⅱ. Studies of Peripheral Circulation by Means of Radioisotope P(32)

Radioisotope P(32) was injected intramuscularly, subcutaneously, and intracutaneously on the lower leg of rabbit before and after ligation of inferior vena cava. Muscle, subcutaneous, and skin circulations were calculated by local clearance method (Kety) in each case. The following results were obtained. 1) Muscle circulation is markedly impeded immediately after ligation and is restored to normal two or three weeks later with gradual improvement. 2) Subcutaneous and skin circulation are not correlated to muscle circulation following ligation. 3) Skin circualtion is accelerated after ligation. 4) Lumbar sympathetic blockade and injection of Imidalin improved muscle circulation following ligation. 5) Influence of ligation of femoral vein on muscle circulation is less than that in the case of inferior vena cava.