Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

骨髄体外組織培養による急性瀉血家兎骨髄の態度に関する研究 第2編 急性瀉血が家兎大腿骨々髄の偽好酸球機能に及ぼす影響に就て

Numamoto, Tetsuro
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The author studied the function of pseudoeosinophils of the femur bone marrow in acute bleeding rabbits from the standpoints of wandering velocity, phagocytosis of carbon particles and vital staining of neutral red; and obtained the following results. 1) Owing to the release of depot blood cells in sinus of bone marrow, the wandering velocity of pseudoeosinophils in the bone marrow slightly increases immediately after and 1 hour after bleeding, but 3-5 hours after bleeding some decrase in wandering velocity and phagocitosis of carbon particles, and deeper staining of vital staining of neutral red can be recognized, namely, some decline in the function of bone-marrow pseudoeosinophils. 2) The wandering velocity of pseudoeosinophils as compared with that in the control starts increasing around 12 hours after bleeding, the time when white corpuscles are reproduced, and the increase in the wandering velocity reaches its maximum at the time when the function of bone marrow is at its best, namely, around 3-5 days after bleeding, while the phagocitosis of carbon particles reaches its lowest level and vital staining of neutral red becomes rapid and deep; and moreover, its decoloration ensues quite rapidly as well. Namely, morphologically mature as they are, nevertheless, these newly produced white corpuscles can be considered as an execessive production of blood cells possessing a peculiar dissociation of function, which is functionally immature.