Studies on the Effect of Cancer on the Pituitary-Adrenocortical System Part II. On the Influence of Cancer on the Anterior Pituitary Glands of Mice

The author studied the cytological changes of anterior pituitary glands in mice inoculated with cancerous materials, and the following findings were observed: 1. In the pituitary of mice with transplanted mammary cancer, acidophil and basophil cells decreased in number, while the chromophobe ones increased in number. 2. Analogous findings were obtained on mice injected with extracts from cancer tissues and urine taken from cancer patients.