Journal of Okayama Medical Association
Published by Okayama Medical Association

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無カタラーゼ血液症における胆汁色素代謝の2,3の検討

Kosaka, Kiyowo
Shimamura, Tokuichi
Hitomi, Yasushi
Thumnail 66_2409.pdf 1.28 MB
Abstract
Certain examinations were done from the aspect of bile pigment metabolism on those people within whose blood there is found almost no catalase, which has resulted as follows: 1. As the hemoglobin quantity estimated for the patient in this disease proving normal, and urinal propendyopent negative, it would not be perfectly true to say that the physical significance for intra-blood-cell catalase serves only as antidestruction due to hemoglobin against H2O2 that has been produced when oxidation in vivo has taken place. 2. In the process to turn bile pigment out of hemoglobin in vitro, when catalase should be in lack, the production of verdohemoglobin feels urged, attaining its height quickly; which, in turn urges a decrease that would happen following it. 3. In the above-mentioned experiment in vitro, generally, l-ascorbic acid helps in main in the production of verdohemoglobin on its initial reaction; successively, participating with velocity toward its destruction, at the brink where verdohemoglobin has reached its top value. 4. The amount respectively of easily split off blood iron, serum iron, as well as blood bilirubin in the tested person's blood, has indicated normal value. Consequently, if it would be surmised from such standpoint as bilirubin metabolism, persons without catalase in their blood might be deemed to be healthy.
ISSN
0030-1558
NCID
AN00032489