Journal of Okayama Medical Association
Published by Okayama Medical Association

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拡大内視鏡検査にて形態変化を観察しえた十二指腸濾胞性リンパ腫の1例

Iwamuro, Masaya Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Takata, Katsuyoshi Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kawano, Seiji Department of Endoscopy, Okayama University Hospital
Kawahara, Yoshiro Department of Endoscopy, Okayama University Hospital
Yoshino, Tadashi Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Okada, Hiroyuki Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Thumnail 128_111.pdf 41.3 MB
Abstract
 A 63-year-old Japanese woman was diagnosed with duodenal follicular lymphoma. The initial esophagogastroduodenoscopic examination with magnifying observation revealed opaque white spots and enlarged whitish villi. Nine months later, esophagogastroduodenoscopy showed that the size of the lymphoma lesion decreased, and only opaque white spots were visible. The histological analysis of biopsy samples obtained during the initial endoscopy examination showed both neoplastic follicles and an inter-follicular infiltration of lymphoma cells, whereas the biopsy samples obtained at the endoscopy performed 9 months later showed only neoplastic follicle formation. These results suggest that the magnifying endoscopic features may reflect the underlying pathological mechanisms : enlarged whitish villi are probably due to lymphoma cell infiltration in the inter-follicular area, and opaque white spots are probably caused by neoplastic follicle formation.
Keywords
消化管原発濾胞性リンパ腫(primary gastrointestinal follicular lymphoma)
悪性リンパ腫(malignant lymphoma)
拡大内視鏡検査(magnifying endoscopy)
Note
症例報告(Case Reports)
ISSN
0030-1558
NCID
AN00032489
DOI
NAID