Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

光トポグラフィーでみられる酸素化ヘモグロビン量の低周波変動の発生源に関する研究

Shoshi, Chikafumi
Ueno, Hiroshi
Kubo, Masako
Oda, Masuko
Hirata, Naoya
Takemoto, Rika
Kinugasa, Kazushi
Okamoto, Motoi
Thumnail 126_117.pdf 1.96 MB
Abstract
There is increasing interest in the intrinsic activity of the resting brain, especially the activity slower than 0.1Hz (i.e., low-frequency oscillations, or LFOs). To investigate the origin of LFOs observed in functional near-infrared spectroscopy (fNIRS), we recorded multichannel fNIRS and electroencephalography (EEG) from the frontal cortex of 11 healthy young volunteers in the resting state. Electrocardiography (ECG), electro-oculography and respiration were also measured. Synchronous oscillations of oxy-hemoglobin (oxy-Hb) around 1.0Hz were detected in all fNIRS channels, and their frequency was consistent with a peak frequency of ECG, suggesting the changes of cerebral blood flow due to heart beats. In addition, oxy-Hb oscillations around 0.1Hz (i.e., LFOs) appeared in the fNIRS. The channels where LFOs appeared differed among the subjects, and the LFOs appeared or disappeared even in the same fNIRS channels. The appearance of LFOs in fNIRS channels was significantly higher when the LFOs appeared on the EEG in the adjacent EEG electrodes compared to when LFOs did not appear on EEG. The amplitude and coherence (synchronicity) of the LFOs were increased by changing the subjects' position from dorsal to the sitting position in both fNIRS and EEG, and the coherence in particular was increased in the homologous fNIRS channels on the bilateral hemispheres. These results suggest that LFOs of oxy-Hb couple with resting-state EEG activity.
Keywords
fNIRS
EEG
LFOs
コヒーレンス解析(Coherence analysis)
連続ウェーブレット解析(continuous wavelet transforms)
Note
原著 (Original Papers)
ISSN
0030-1558
NCID
AN00032489
DOI
NAID