Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.


Maeda, Naoaki
Koujima, Takeshi
Ohara, Toshiaki
Tanabe, Shunsuke
Noma, Kazuhiro Kaken ID researchmap
Sakurama, Kazuhumi
Fujiwara, Toshiyosi ORCID Kaken ID
Thumnail 126_39.pdf 3.34 MB
 Esophageal endocrine cell carcinoma is extremely rare. We report a case of esophageal endocrine cell carcinoma showing histological complete response to neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil (DCF). A 66-year-old man had been experiencing epigastralgia, and a type 2 tumor in the thoracic part of esophagus was detected by upper endoscopy. The biopsy showed endocrine cell carcinoma. PET/CT, endoscopy and an esophagogram showed that the patient had a 70-mm scaled type 2 tumor in the middle thoracic esophagus, and they also revealed lymph node metastases (no. 106recR). We diagnosed a cT3cN1cM0 cStage III tumor. With two courses of DCF treatment, both the primary tumor and lymph node metastases showed a partial response. We performed a subtotal esophagectomy with three-field lymph node dissection. The pathological examination of the resected specimens revealed no malignant cells in the esophagus or lymph nodes, and we concluded that the pathological effect of the DCF treatment was Grade 3.
食道癌(esophageal cancer)
内分泌細胞癌(endocrine cell carcinoma)
DCF療法(DCF treatment)
症例報告 (Case Reports)