Journal of Okayama Medical Association
Published by Okayama Medical Association

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メサラジン坐薬調製の工夫と臨床経験

Funagakure, Keiko
Horita, Syuzi
Hamaoka, Terutaka
Tasaka, Takeshi
Tatibana, Hiroshi
Murakami, Takako
Toyokawa, Tatuya
Sato, Eiji
Tomoda, Jun
Thumnail 125_29.pdf 4.66 MB
Abstract
Ulcerative proctitis (UP) is a prevalent condition associated with increased morbidity, and topical mesalazine (5-aminosalicylic acid [5-ASA]) is known to inhibit the inflammatory processes in UP. We successfully devised mesalazine suppositories, in which 250mg mesalazine was equally distributed and remained stable for at least 2 weeks. We evaluated the effect of using mesalazine suppositories twice a day (BID) on two UP patients. The results demonstrated that mesalazine suppositories were efficacious, well tolerated and safe for the long-term maintenance of UP remission.
Keywords
メサラジン坐薬(mesalazine suppositories)
潰瘍性大腸炎直腸型(ulcerative proctitis)
Note
原著(Original Paper)
ISSN
0030-1558
NCID
AN00032489
DOI