Journal of Okayama Medical Association
Published by Okayama Medical Association

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MRIによる肥大型心筋症の局所左室壁収縮動態の評価

Sato, Tetsuya
106_239.pdf 2.35 MB
Abstract
To assess the regional myocardial function in hypertrophic cardiomyopathy (HCM), I examined the systolic wall thickening (% WT) and percent change of segmental wall area (% AR) using cine magnetic resonance imaging in 23 normal volunteers (G1) and 40 patients (G2) with HCM. Short axis images of the left ventricle were recorded at the base and the apex, and were divided into 5 segments, and % WT and % AR were measured for each segment. There were no significant differences in % WT and % AR among the segments in G1, while % WT of the posterior septum, posterior and lateral segments in the apex were higher than the according to end-diastolic wall thickness : G2a, ≦12mm ; G2b, 12<≦15 ; G2c, >15. At each slice level, % WT and % AR were highest in G2a and lowest in G2c. These findings suggest that myocardial shortening in normal subjects is higher in the apex than in the base, and, in HCM, regional myocardial function decreases in association with an advance of hypertrophy, with a possible compensatory increased wall function of normal segments.
Keywords
cine MRI
hypertrophic cardimyopathy
regional myocardial function
percrnt wall thickening
percent change of segmental wall area
Note
原著
ISSN
0030-1558
NCID
AN00032489