Journal of Okayama Medical Association
Published by Okayama Medical Association

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NIH 3T3 細胞の温熱耐性に対するケルセチンの作用 第1編 細胞の生存率からみたケルセチンの作用

Hiraki, Yoshio
Kawasaki, Shouji
Thumnail 103_973.pdf 465 KB
Abstract
The inhibition of thermotolerance development by quercetin was examined in NIH 3T3 cells. The cytotoxicity of quercetin increased with the increase in the concentration (10,100μg/ml) and duration (12,48,72 hours) of treatment. The cell killing effect of heat was not enhanced by quercetin (10μg/ml) itself. Quercetin (10μg/ml) inhibited the proliferation of cells for about 72 hours. Quercetin (10μg/ml) delayed the development of thermotolerance, but did not decrease the degree of maximum thermotolerance. Quercetin (10μg/ml) exibited no effect on the decay of thermotolerance.
Keywords
ケルセチン
温熱耐性
温熱療法
Note
原著
ISSN
0030-1558
NCID
AN00032489