Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

分化型甲状腺癌転移巣の検出における(201)Tl-chlorideシンチグラフィの有用性と(131)I内用療法の経験

Kawasaki, Yukiko
Tanabe, Masatada
Tamai, Toyosato
Ohkawa, Motoomi
Takashima, Hitoshi
Kojima, Kanji
Satoh, Katashi
Seo, Hiroyuki
Hosokawa, Nobuyuki
Matsuno, Shinsuke
Miyamoto, Tsutomu
Sakamoto, Kazuhiro
Gohda, Fuminori
Hino, Ichiroh
Kawase, Yoshiroh
100_981.pdf 3.4 MB
Abstract
The aim of this study was to compare T1-201 scintigraphy with I-131 scintigraphy and to assess whether T1-201 scintigraphy has diagnostic advantages in detecting metastasis of patients with thyroid carcinoma. All patients had undergone total thyroidectomy or suhthyroidectomy. The study population included 4 men and 11 women, with ages ranging from 11-69 years. Eight had follicular adenocarcinomas, and 7 had papillary adenocarcinomas (including mixed papillary-follicular). The positive detection rate of both T1-201 and I-131 scintigraphy was 67%, which correlated with the histological type (75% of papillary type and 63% of follicular type).T1-201 scintigraphy has the advantage of detecting non-functioning metastases. On the other hand, I-131 scintigraphy has the advantage of detecting occult functioning metastases.Factors affecting the effect of radioiodine treatment for metastasis of 15 patients with differentiated thyroid cancer were studied. We evaluated the effect of I-131 treatment by the degree of I-131 accumulation shown on the scintigram. The degree of I-131 uptake in metastases was related to age, histology and type of metastatic lesion. Good I-131 uptake in metastases was found in patients less than 40 years old, with papillary adenocarcinoma and without bone metastasis.
Keywords
分化型甲状腺癌
(201)Tl-chlorideシンチグラフィ
(131)I内用療法
ISSN
0030-1558
NCID
AN00032489