Preparation of Biodegradable Polymer Microcapsules Enclosing Anti-mite Agent

Many kinds of mite was caused by allergy and sick house syndrome, so it has become one of the social problems. Farnesyl acetone is one of the most potent anti-mite agent. However the vapor pressure of farnesyl acetone is high even at room temperature. This indicates the anti-mite effect has not been sustained even though the agent has strong anti-mite effect. In this study, we attempted to prepare polylactide microcapsule with farnesyl acetone for the purpose of sustainable dosage form of anti-mite agent. Microcapsule was prepared by solvent evaporation, which was a method of microencapsulation. The effects of preparation conditions on the enclosing efficiency, the release of microcapsule and anti-mite effect of microcapsule were investigated.