Acta Medica Okayama volume74 issue3
2020-06 発行

Intravenous Vitamin C as Ancillary Treatment for Cranial Polyneuritis and Meningitis due to Varicella Zoster Virus Reactivation

Hongo, Takashi Department of Emergency Medicine, Okayama Saiseikai General Hospital
Ikeda, Fusao Department of Internal Medicine, Okayama Saiseikai General Hospital
Fujioka, Shinichi Department of Internal Medicine, Okayama Saiseikai General Hospital
Akatsuka, Riku Department of Internal Medicine, Okayama Saiseikai General Hospital
Fujiwara, Tosifumi Department of Emergency Medicine, Okayama Saiseikai General Hospital
Yamamoto, Kazuhide Department of Internal Medicine, Okayama Saiseikai General Hospital
Publication Date
2020-06
Abstract
A 65-year-old Japanese woman developed vesicular eruptions on her right ear due to varicella zoster virus (VZV) reactivation, followed by cranial polyneuritis and meningitis affecting her right cranial nerves V, VII, VIII, IX, and X. After acyclovir administration, her facial paralysis worsened. Intravenous methylprednisolone and vitamin C were administered on Day 4 post-admission. Her symptoms steadily improved, and by Day 45 she had fully recovered. Cranial polyneuritis is a rare complication of VZV reactivation, and there is no established method of treatment. This is the first report of full recovery from cranial polyneuritis using intravenous vitamin C as ancillary treatment.
Document Type
Case Report
Keywords
varicella zoster virus
polyneuritis
vitamin C
meningitis
facial nerve palsy
Link to PubMed
Thumnail 74_3_257.pdf 2.81 MB