Acta Medica Okayama volume73 issue5
2019-10 発行

Relationship between Sedentary Behavior and All-cause Mortality in Japanese Chronic Hemodialysis Patients: A Prospective Cohort Study

Hishii, Shuhei Department of Hygiene, Faculty of Medicine, Kagawa University
Miyatake, Nobuyuki Department of Hygiene, Faculty of Medicine, Kagawa University
Nishi, Hiroyuki Innoshima General Hospital
Katayama, Akihiko Faculty of Social Studies, Shikokugakuin University
Ujike, Kazuhiro Innoshima General Hospital
Koumoto, Kiichi Innoshima General Hospital
Suzuki, Hiromi Department of Hygiene, Faculty of Medicine, Kagawa University
Hashimoto, Hiroo Innoshima General Hospital
Publication Date
2019-10
Abstract
We investigated the relationship between sedentary behavior and all-cause mortality in patients undergoing hemodialysis. A total of 71 patients (39 men, 32 women, aged 72.1±11.7 years) were enrolled in this longitudinal study. Their sedentary behavior was measured using a tri-accelerometer that provides relative values per daily wearing time. We classified the sedentary behavior time into 2 groups (under the median: short-sedentary behavior (SB) group; over the median: long-SB group) and compared the groups’ clinical parameters. We compared the groups’ survival rates by using Kaplan-Meier curves and the log-rank test, and we performed multivariate analyses by a Cox-proportional hazard model to evaluate the relationship between the sedentary behavior and the survival rate. Twenty patients (28.2%) died during the observation period. The survival rate of the short-SB group was significantly higher than that of the long-SB group. Sedentary behavior was thus an important factor for all-cause mortality even after adjusting for confounding factors by a Cox-proportional hazard model. Sedentary behavior is closely linked to all-cause mortality, especially total days and non-hemodialysis days, and reducing sedentary behavior may be beneficial to reduce the all-cause mortality of patients on chronic hemodialysis.
Document Type
Original Article
Keywords
sedentary behavior
hemodialysis
mortality
physical activity
Link to PubMed
Thumnail 73_5_419.pdf 2.07 MB