Acta Medica Okayama volume73 issue5
2019-10 発行

Feasibility of Laparoscopic Radical Cystectomy in Elderly Patients: A Comparative Analysis of Clinical Outcomes in a Single Institution

Yanagihara, Yutaka Department of Urology, Ehime University Medical School
Nishida, Keigo Department of Urology, Ehime University Medical School
Watanabe, Ryuta Department of Urology, Ehime University Medical School
Koyama, Kanae Department of Urology, Ehime University Medical School
Sawada, Yuichiro Department of Urology, Ehime University Medical School
Noda, Terutaka
Asai, Seiji Department of Urology, Ehime University Medical School
Fukumoto, Tetsuya Department of Urology, Ehime University Medical School
Miura, Noriyoshi Department of Urology, Ehime University Medical School
Miyauchi, Yuki Department of Urology, Ehime University Medical School
Kikugawa, Tadahiko Department of Urology, Ehime University Medical School
Saika, Takashi Department of Urology, Ehime University Medical School
Publication Date
2019-10
Abstract
Laparoscopic radical cystectomy (LRC) is a standard surgical treatment for muscle-invasive bladder cancer and high-risk non-muscle-invasive bladder cancer. LRC is a less invasive modality than conventional open surgery. Therefore, even elderly patients with invasive bladder cancer may be candidates for LRC. In this study, a comparative analysis of perioperative/oncological outcomes between elderly patients and younger patients who underwent LRC was performed to assess the feasibility of LRC in elderly patients. Sixty-eight consecutive patients who underwent LRC between October 2013 and March 2018 were enrolled and stratified into those younger than 75 years (n=37) and those ≥ 75 years old (n=31). The median follow-up period was 28.2 months. The preoperative and operative parameters and complications were similar in both groups. The 2-year overall survival (OS) was 64.4% in the younger vs. 76.4% in the elderly group (p=0.053), cancer-specific survival (CSS) was 79.3% vs. 81.7% (p=0.187), and recurrence-free survival (RFS) was 58.2% vs. 75.7% (p=0.174), respectively. No significant differences were observed in OS, CSS, or RFS between the groups. No significant differences were found between the groups with respect to peri-surgical/oncological outcomes. We conclude that LRC is feasible in elderly patients.
Document Type
Original Article
Keywords
bladder cancer
laparoscopic surgery
radical cystectomy
elderly patient
Link to PubMed
Thumnail 73_5_413.pdf 2.03 MB